Receptor of activated protein C kinase 1
Intramolecular
Cysteine 240 and cysteine 249 L
Cysteine 153 and cysteine 168 L
Cysteine 138 and cysteine 182 L
Cysteine 153 and cysteine 207 L
Cysteine 249 and cysteine 286 L
Cysteine 168 and cysteine 207 L
Cysteine 240 and cysteine 286 L
4aow B 240 B 249
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 240 and 249.
Details
Redox score ?
60
PDB code
4aow
Structure name
crystal structure of the human rack1 protein at a resolution of 2
Structure deposition date
2012-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
91
Minimum pKa ?
8
% buried
100
Peptide accession
P63244
Residue number A
240
Residue number B
249
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 240 of Receptor of activated protein C kinase 1
Cysteine 249 of Receptor of activated protein C kinase 1
4aow A 153 A 168
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 153 and 168. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
4aow
Structure name
crystal structure of the human rack1 protein at a resolution of 2
Structure deposition date
2012-03-30
Thiol separation (Å)
5
Half-sphere exposure sum ?
98
Minimum pKa ?
10
% buried
100
Peptide accession
P63244
Residue number A
153
Residue number B
168
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 153 of Receptor of activated protein C kinase 1
Cysteine 168 of Receptor of activated protein C kinase 1
4aow C 138 C 182
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 138 and 182. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
4aow
Structure name
crystal structure of the human rack1 protein at a resolution of 2
Structure deposition date
2012-03-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
34
Peptide accession
P63244
Residue number A
138
Residue number B
182
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 138 of Receptor of activated protein C kinase 1
Cysteine 182 of Receptor of activated protein C kinase 1
4aow B 153 B 207
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 153 and 207. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
4aow
Structure name
crystal structure of the human rack1 protein at a resolution of 2
Structure deposition date
2012-03-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
95
Minimum pKa ?
6
% buried
100
Peptide accession
P63244
Residue number A
153
Residue number B
207
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 153 of Receptor of activated protein C kinase 1
Cysteine 207 of Receptor of activated protein C kinase 1
6g5h g 249 g 286
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 249 and 286. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
6g5h
Structure name
cryo-em structure of a late human pre-40s ribosomal subunit - mature
Structure deposition date
2018-03-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
85
Minimum pKa ?
12
% buried
98
Peptide accession
P63244
Residue number A
249
Residue number B
286
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 249 of Receptor of activated protein C kinase 1
Cysteine 286 of Receptor of activated protein C kinase 1
4aow C 168 C 207
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 168 and 207. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
4aow
Structure name
crystal structure of the human rack1 protein at a resolution of 2
Structure deposition date
2012-03-30
Thiol separation (Å)
8
Half-sphere exposure sum ?
94
Minimum pKa ?
13
% buried
100
Peptide accession
P63244
Residue number A
168
Residue number B
207
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 168 of Receptor of activated protein C kinase 1
Cysteine 207 of Receptor of activated protein C kinase 1
4aow B 240 B 286
A redox-regulated disulphide may form within Receptor of activated protein C kinase 1 between cysteines 240 and 286. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
28
PDB code
4aow
Structure name
crystal structure of the human rack1 protein at a resolution of 2
Structure deposition date
2012-03-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
84
Minimum pKa ?
12
% buried
100
Peptide accession
P63244
Residue number A
240
Residue number B
286
Peptide name
Receptor of activated protein C kinase 1
Ligandability
Cysteine 240 of Receptor of activated protein C kinase 1
Cysteine 286 of Receptor of activated protein C kinase 1
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