Protein jagged-1
Intramolecular
Cysteine 271 and cysteine 282
Cysteine 324 and cysteine 333
Cysteine 234 and cysteine 245
Cysteine 238 and cysteine 251
Cysteine 306 and cysteine 322
Cysteine 300 and cysteine 312
Cysteine 284 and cysteine 293
Cysteine 220 and cysteine 229
Cysteine 200 and cysteine 212
Cysteine 265 and cysteine 276
More...Cysteine 54 and cysteine 66
Cysteine 253 and cysteine 262
Cysteine 55 and cysteine 71
Cysteine 187 and cysteine 196
Cysteine 78 and cysteine 92
Cysteine 251 and cysteine 262
Cysteine 282 and cysteine 293
Cysteine 306 and cysteine 312
Cysteine 271 and cysteine 293
Cysteine 234 and cysteine 238
Cysteine 322 and cysteine 333
Cysteine 312 and cysteine 322
Cysteine 238 and cysteine 262
Cysteine 306 and cysteine 333
Cysteine 251 and cysteine 253
Cysteine 282 and cysteine 284
Cysteine 322 and cysteine 324
Cysteine 238 and cysteine 245
Cysteine 300 and cysteine 306
Cysteine 234 and cysteine 251
Cysteine 271 and cysteine 284
Cysteine 306 and cysteine 324
Cysteine 245 and cysteine 251
Cysteine 300 and cysteine 322
Cysteine 238 and cysteine 253
Cysteine 271 and cysteine 276
Cysteine 265 and cysteine 282
Cysteine 55 and cysteine 66
Cysteine 66 and cysteine 71
Cysteine 276 and cysteine 284
2vj2 A 271 A 282
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 271 and 282.
Details
Redox score ?
88
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
271
Residue number B
282
Peptide name
Protein jagged-1
Ligandability
Cysteine 271 of Protein jagged-1
Cysteine 282 of Protein jagged-1
2vj2 A 324 A 333
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 324 and 333.
Details
Redox score ?
88
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
324
Residue number B
333
Peptide name
Protein jagged-1
Ligandability
Cysteine 324 of Protein jagged-1
Cysteine 333 of Protein jagged-1
4cbz A 234 A 245
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 234 and 245.
Details
Redox score ?
88
PDB code
4cbz
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
234
Residue number B
245
Peptide name
Protein jagged-1
Ligandability
Cysteine 234 of Protein jagged-1
Cysteine 245 of Protein jagged-1
5bo1 B 238 B 251
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 238 and 251.
Details
Redox score ?
88
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
238
Residue number B
251
Peptide name
Protein jagged-1
Ligandability
Cysteine 238 of Protein jagged-1
Cysteine 251 of Protein jagged-1
5bo1 B 306 B 322
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 306 and 322.
Details
Redox score ?
88
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
306
Residue number B
322
Peptide name
Protein jagged-1
Ligandability
Cysteine 306 of Protein jagged-1
Cysteine 322 of Protein jagged-1
5bo1 A 300 A 312
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 300 and 312.
Details
Redox score ?
87
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
300
Residue number B
312
Peptide name
Protein jagged-1
Ligandability
Cysteine 300 of Protein jagged-1
Cysteine 312 of Protein jagged-1
2vj2 A 284 A 293
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 284 and 293.
Details
Redox score ?
87
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
284
Residue number B
293
Peptide name
Protein jagged-1
Ligandability
Cysteine 284 of Protein jagged-1
Cysteine 293 of Protein jagged-1
2vj2 A 220 A 229
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 220 and 229.
Details
Redox score ?
87
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
220
Residue number B
229
Peptide name
Protein jagged-1
Ligandability
Cysteine 220 of Protein jagged-1
Cysteine 229 of Protein jagged-1
2vj2 B 200 B 212
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 200 and 212.
Details
Redox score ?
86
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
200
Residue number B
212
Peptide name
Protein jagged-1
Ligandability
Cysteine 200 of Protein jagged-1
Cysteine 212 of Protein jagged-1
5bo1 B 265 B 276
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 265 and 276.
Details
Redox score ?
86
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
265
Residue number B
276
Peptide name
Protein jagged-1
Ligandability
Cysteine 265 of Protein jagged-1
Cysteine 276 of Protein jagged-1
4cc0 A 54 A 66
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 54 and 66.
Details
Redox score ?
85
PDB code
4cc0
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
54
Residue number B
66
Peptide name
Protein jagged-1
Ligandability
Cysteine 54 of Protein jagged-1
Cysteine 66 of Protein jagged-1
5bo1 A 253 A 262
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 253 and 262.
Details
Redox score ?
85
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
253
Residue number B
262
Peptide name
Protein jagged-1
Ligandability
Cysteine 253 of Protein jagged-1
Cysteine 262 of Protein jagged-1
5uk5 B 55 B 71
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 55 and 71.
Details
Redox score ?
85
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
55
Residue number B
71
Peptide name
Protein jagged-1
Ligandability
Cysteine 55 of Protein jagged-1
Cysteine 71 of Protein jagged-1
5uk5 B 187 B 196
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 187 and 196.
Details
Redox score ?
84
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
187
Residue number B
196
Peptide name
Protein jagged-1
Ligandability
Cysteine 187 of Protein jagged-1
Cysteine 196 of Protein jagged-1
4cbz B 78 B 92
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 78 and 92.
Details
Redox score ?
81
PDB code
4cbz
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
78
Residue number B
92
Peptide name
Protein jagged-1
Ligandability
Cysteine 78 of Protein jagged-1
Cysteine 92 of Protein jagged-1
5bo1 B 251 B 262
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 251 and 262.
Details
Redox score ?
76
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
251
Residue number B
262
Peptide name
Protein jagged-1
Ligandability
Cysteine 251 of Protein jagged-1
Cysteine 262 of Protein jagged-1
4cbz A 282 A 293
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 282 and 293.
Details
Redox score ?
76
PDB code
4cbz
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
282
Residue number B
293
Peptide name
Protein jagged-1
Ligandability
Cysteine 282 of Protein jagged-1
Cysteine 293 of Protein jagged-1
4cbz A 306 A 312
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 306 and 312.
Details
Redox score ?
75
PDB code
4cbz
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
306
Residue number B
312
Peptide name
Protein jagged-1
Ligandability
Cysteine 306 of Protein jagged-1
Cysteine 312 of Protein jagged-1
2vj2 A 271 A 293
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 271 and 293.
Details
Redox score ?
75
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
271
Residue number B
293
Peptide name
Protein jagged-1
Ligandability
Cysteine 271 of Protein jagged-1
Cysteine 293 of Protein jagged-1
4cc0 A 234 A 238
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 234 and 238.
Details
Redox score ?
73
PDB code
4cc0
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
234
Residue number B
238
Peptide name
Protein jagged-1
Ligandability
Cysteine 234 of Protein jagged-1
Cysteine 238 of Protein jagged-1
4cbz A 322 A 333
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 322 and 333.
Details
Redox score ?
71
PDB code
4cbz
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
322
Residue number B
333
Peptide name
Protein jagged-1
Ligandability
Cysteine 322 of Protein jagged-1
Cysteine 333 of Protein jagged-1
5bo1 A 312 A 322
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 312 and 322.
Details
Redox score ?
71
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
5
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
312
Residue number B
322
Peptide name
Protein jagged-1
Ligandability
Cysteine 312 of Protein jagged-1
Cysteine 322 of Protein jagged-1
4cc1 A 238 A 262
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 238 and 262.
Details
Redox score ?
70
PDB code
4cc1
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
5
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
238
Residue number B
262
Peptide name
Protein jagged-1
Ligandability
Cysteine 238 of Protein jagged-1
Cysteine 262 of Protein jagged-1
4cc1 A 306 A 333
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 306 and 333.
Details
Redox score ?
69
PDB code
4cc1
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
5
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
306
Residue number B
333
Peptide name
Protein jagged-1
Ligandability
Cysteine 306 of Protein jagged-1
Cysteine 333 of Protein jagged-1
5uk5 B 251 B 253
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 251 and 253.
Details
Redox score ?
67
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
251
Residue number B
253
Peptide name
Protein jagged-1
Ligandability
Cysteine 251 of Protein jagged-1
Cysteine 253 of Protein jagged-1
5uk5 B 282 B 284
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 282 and 284.
Details
Redox score ?
66
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
282
Residue number B
284
Peptide name
Protein jagged-1
Ligandability
Cysteine 282 of Protein jagged-1
Cysteine 284 of Protein jagged-1
5uk5 B 322 B 324
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 322 and 324.
Details
Redox score ?
66
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
6
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
322
Residue number B
324
Peptide name
Protein jagged-1
Ligandability
Cysteine 322 of Protein jagged-1
Cysteine 324 of Protein jagged-1
4cc0 B 238 B 245
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 238 and 245.
Details
Redox score ?
65
PDB code
4cc0
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
6
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
238
Residue number B
245
Peptide name
Protein jagged-1
Ligandability
Cysteine 238 of Protein jagged-1
Cysteine 245 of Protein jagged-1
4cbz A 300 A 306
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 300 and 306.
Details
Redox score ?
63
PDB code
4cbz
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
300
Residue number B
306
Peptide name
Protein jagged-1
Ligandability
Cysteine 300 of Protein jagged-1
Cysteine 306 of Protein jagged-1
2vj2 B 234 B 251
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 234 and 251.
Details
Redox score ?
62
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
234
Residue number B
251
Peptide name
Protein jagged-1
Ligandability
Cysteine 234 of Protein jagged-1
Cysteine 251 of Protein jagged-1
2vj2 B 271 B 284
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 271 and 284.
Details
Redox score ?
60
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
271
Residue number B
284
Peptide name
Protein jagged-1
Ligandability
Cysteine 271 of Protein jagged-1
Cysteine 284 of Protein jagged-1
4cc0 A 306 A 324
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 306 and 324.
Details
Redox score ?
60
PDB code
4cc0
Structure name
notch ligand, jagged-1, contains an n-terminal c2 domain
Structure deposition date
2013-10-17
Thiol separation (Å)
7
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
306
Residue number B
324
Peptide name
Protein jagged-1
Ligandability
Cysteine 306 of Protein jagged-1
Cysteine 324 of Protein jagged-1
5bo1 A 245 A 251
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 245 and 251.
Details
Redox score ?
60
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
6
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
245
Residue number B
251
Peptide name
Protein jagged-1
Ligandability
Cysteine 245 of Protein jagged-1
Cysteine 251 of Protein jagged-1
5bo1 A 300 A 322
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 300 and 322. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
300
Residue number B
322
Peptide name
Protein jagged-1
Ligandability
Cysteine 300 of Protein jagged-1
Cysteine 322 of Protein jagged-1
5bo1 A 238 A 253
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 238 and 253. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
5bo1
Structure name
crystal structure of a human jag1 fragment in complex with an anti- jag1 fab
Structure deposition date
2015-05-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
238
Residue number B
253
Peptide name
Protein jagged-1
Ligandability
Cysteine 238 of Protein jagged-1
Cysteine 253 of Protein jagged-1
2vj2 A 271 A 276
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 271 and 276. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
2vj2
Structure name
human jagged-1, domains dsl and egfs1-3
Structure deposition date
2007-12-06
Thiol separation (Å)
8
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
271
Residue number B
276
Peptide name
Protein jagged-1
Ligandability
Cysteine 271 of Protein jagged-1
Cysteine 276 of Protein jagged-1
2kb9 A 14 A 31
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 265 and 282 (14 and 31 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
2kb9
Structure name
human jagged-1, exon 6
Structure deposition date
2008-11-24
Thiol separation (Å)
7
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
265
Residue number B
282
Peptide name
Protein jagged-1
Ligandability
Cysteine 265 of Protein jagged-1
Cysteine 282 of Protein jagged-1
5uk5 B 55 B 66
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 55 and 66. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
55
Residue number B
66
Peptide name
Protein jagged-1
Ligandability
Cysteine 55 of Protein jagged-1
Cysteine 66 of Protein jagged-1
5uk5 B 66 B 71
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 66 and 71. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
5uk5
Structure name
complex of notch1(egf8-12) bound to jagged1(n-egf3)
Structure deposition date
2017-01-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63722
Residue number A
66
Residue number B
71
Peptide name
Protein jagged-1
Ligandability
Cysteine 66 of Protein jagged-1
Cysteine 71 of Protein jagged-1
2kb9 A 25 A 33
A redox-regulated disulphide may form within Protein jagged-1 between cysteines 276 and 284 (25 and 33 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2kb9
Structure name
human jagged-1, exon 6
Structure deposition date
2008-11-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
P78504
Residue number A
276
Residue number B
284
Peptide name
Protein jagged-1
Ligandability
Cysteine 276 of Protein jagged-1
Cysteine 284 of Protein jagged-1
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