ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S35, mitochondrial

Intramolecular
Cysteine 123 and cysteine 130
A redox-regulated disulphide may form within 28S ribosomal protein S35, mitochondrial between cysteines 123 and 130. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
8css
Structure name
human mitochondrial small subunit assembly intermediate (state d)
Structure deposition date
2022-05-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
11
% buried
84
Peptide accession
P82673
Residue number A
123
Residue number B
130
Peptide name
28S ribosomal protein S35, mitochondrial

Ligandability

Cysteine 123 of 28S ribosomal protein S35, mitochondrial

Cysteine 130 of 28S ribosomal protein S35, mitochondrial

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