ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S5, mitochondrial

Intramolecular
Cysteine 316 and cysteine 324
A redox-regulated disulphide may form within 28S ribosomal protein S5, mitochondrial between cysteines 316 and 324. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
8css
Structure name
human mitochondrial small subunit assembly intermediate (state d)
Structure deposition date
2022-05-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
80
Minimum pKa ?
12
% buried
100
Peptide accession
P82675
Residue number A
316
Residue number B
324
Peptide name
28S ribosomal protein S5, mitochondrial

Ligandability

Cysteine 316 of 28S ribosomal protein S5, mitochondrial

Cysteine 324 of 28S ribosomal protein S5, mitochondrial

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