Low-density lipoprotein receptor-related protein 2
Intramolecular
Cysteine 3863 and cysteine 1395
Cysteine 1354 and cysteine 1365
Cysteine 3993 and cysteine 4007
Cysteine 229 and cysteine 247
Cysteine 3124 and cysteine 3137
Cysteine 1361 and cysteine 1374
Cysteine 3116 and cysteine 3128
Cysteine 3084 and cysteine 3102
Cysteine 3034 and cysteine 3046
Cysteine 241 and cysteine 256
More...Cysteine 2354 and cysteine 2369
Cysteine 87 and cysteine 103
Cysteine 3139 and cysteine 3152
Cysteine 3521 and cysteine 3540
Cysteine 351 and cysteine 361
Cysteine 1320 and cysteine 1339
Cysteine 3741 and cysteine 3756
Cysteine 1032 and cysteine 1050
Cysteine 331 and cysteine 345
Cysteine 1116 and cysteine 1134
Cysteine 2761 and cysteine 2776
Cysteine 4013 and cysteine 4023
Cysteine 4403 and cysteine 4412
Cysteine 1376 and cysteine 1389
Cysteine 3014 and cysteine 3029
Cysteine 265 and cysteine 278
Cysteine 1208 and cysteine 1223
Cysteine 1169 and cysteine 1184
Cysteine 1195 and cysteine 1214
Cysteine 1395 and cysteine 1405
Cysteine 28 and cysteine 40
Cysteine 1291 and cysteine 1306
Cysteine 47 and cysteine 62
Cysteine 2995 and cysteine 3007
Cysteine 3972 and cysteine 3981
Cysteine 1128 and cysteine 1143
Cysteine 222 and cysteine 234
Cysteine 3937 and cysteine 3955
Cysteine 202 and cysteine 217
Cysteine 2801 and cysteine 2818
8em4 B 3863 B 3880
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3863 and 1395 (3863 and 3880 respectively in this structure).
Details
Redox score ?
90
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3863
Residue number B
1395
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3863 of Low-density lipoprotein receptor-related protein 2
Cysteine 1395 of Low-density lipoprotein receptor-related protein 2
8em4 A 1354 A 1365
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1354 and 1365.
Details
Redox score ?
90
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1354
Residue number B
1365
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1354 of Low-density lipoprotein receptor-related protein 2
Cysteine 1365 of Low-density lipoprotein receptor-related protein 2
8em4 A 3993 A 4007
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3993 and 4007.
Details
Redox score ?
89
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3993
Residue number B
4007
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3993 of Low-density lipoprotein receptor-related protein 2
Cysteine 4007 of Low-density lipoprotein receptor-related protein 2
8em4 B 229 B 247
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 229 and 247.
Details
Redox score ?
89
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
229
Residue number B
247
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 229 of Low-density lipoprotein receptor-related protein 2
Cysteine 247 of Low-density lipoprotein receptor-related protein 2
8em4 B 3124 B 3137
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3124 and 3137.
Details
Redox score ?
89
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3124
Residue number B
3137
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3124 of Low-density lipoprotein receptor-related protein 2
Cysteine 3137 of Low-density lipoprotein receptor-related protein 2
8em4 B 1361 B 1374
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1361 and 1374.
Details
Redox score ?
89
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1361
Residue number B
1374
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1361 of Low-density lipoprotein receptor-related protein 2
Cysteine 1374 of Low-density lipoprotein receptor-related protein 2
8em7 A 3116 A 3128
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3116 and 3128.
Details
Redox score ?
89
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3116
Residue number B
3128
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3116 of Low-density lipoprotein receptor-related protein 2
Cysteine 3128 of Low-density lipoprotein receptor-related protein 2
8em4 A 3084 A 3102
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3084 and 3102.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3084
Residue number B
3102
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3084 of Low-density lipoprotein receptor-related protein 2
Cysteine 3102 of Low-density lipoprotein receptor-related protein 2
8em4 A 3034 A 3046
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3034 and 3046.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3034
Residue number B
3046
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3034 of Low-density lipoprotein receptor-related protein 2
Cysteine 3046 of Low-density lipoprotein receptor-related protein 2
8em7 B 241 B 256
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 241 and 256.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
241
Residue number B
256
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 241 of Low-density lipoprotein receptor-related protein 2
Cysteine 256 of Low-density lipoprotein receptor-related protein 2
8em7 A 2354 A 2369
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 2354 and 2369.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
2354
Residue number B
2369
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 2354 of Low-density lipoprotein receptor-related protein 2
Cysteine 2369 of Low-density lipoprotein receptor-related protein 2
8em4 B 87 B 103
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 87 and 103.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
87
Residue number B
103
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 87 of Low-density lipoprotein receptor-related protein 2
Cysteine 103 of Low-density lipoprotein receptor-related protein 2
8em4 B 3139 B 3152
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3139 and 3152.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3139
Residue number B
3152
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3139 of Low-density lipoprotein receptor-related protein 2
Cysteine 3152 of Low-density lipoprotein receptor-related protein 2
8em4 A 3521 A 3540
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3521 and 3540.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3521
Residue number B
3540
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3521 of Low-density lipoprotein receptor-related protein 2
Cysteine 3540 of Low-density lipoprotein receptor-related protein 2
8em4 B 351 B 361
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 351 and 361.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
351
Residue number B
361
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 351 of Low-density lipoprotein receptor-related protein 2
Cysteine 361 of Low-density lipoprotein receptor-related protein 2
8em7 A 1320 A 1339
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1320 and 1339.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1320
Residue number B
1339
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1320 of Low-density lipoprotein receptor-related protein 2
Cysteine 1339 of Low-density lipoprotein receptor-related protein 2
8em4 B 3741 B 3756
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3741 and 3756.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
39
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3741
Residue number B
3756
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3741 of Low-density lipoprotein receptor-related protein 2
Cysteine 3756 of Low-density lipoprotein receptor-related protein 2
8em7 B 1032 B 1050
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1032 and 1050.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1032
Residue number B
1050
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1032 of Low-density lipoprotein receptor-related protein 2
Cysteine 1050 of Low-density lipoprotein receptor-related protein 2
8em4 A 331 A 345
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 331 and 345.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
331
Residue number B
345
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 331 of Low-density lipoprotein receptor-related protein 2
Cysteine 345 of Low-density lipoprotein receptor-related protein 2
2m0p A 1116 A 1134
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1116 and 1134.
Details
Redox score ?
88
PDB code
2m0p
Structure name
solution structure of the tenth complement type repeat of human megalin
Structure deposition date
2012-11-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P98164
Residue number A
1116
Residue number B
1134
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1116 of Low-density lipoprotein receptor-related protein 2
Cysteine 1134 of Low-density lipoprotein receptor-related protein 2
8em7 A 2761 A 2776
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 2761 and 2776.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
39
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
2761
Residue number B
2776
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 2761 of Low-density lipoprotein receptor-related protein 2
Cysteine 2776 of Low-density lipoprotein receptor-related protein 2
8em4 B 4013 B 4023
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 4013 and 4023.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
4013
Residue number B
4023
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 4013 of Low-density lipoprotein receptor-related protein 2
Cysteine 4023 of Low-density lipoprotein receptor-related protein 2
8em4 A 4403 A 4412
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 4403 and 4412.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
4403
Residue number B
4412
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 4403 of Low-density lipoprotein receptor-related protein 2
Cysteine 4412 of Low-density lipoprotein receptor-related protein 2
8em4 B 1376 B 1389
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1376 and 1389.
Details
Redox score ?
88
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1376
Residue number B
1389
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1376 of Low-density lipoprotein receptor-related protein 2
Cysteine 1389 of Low-density lipoprotein receptor-related protein 2
8em7 B 3014 B 3029
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3014 and 3029.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
40
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3014
Residue number B
3029
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3014 of Low-density lipoprotein receptor-related protein 2
Cysteine 3029 of Low-density lipoprotein receptor-related protein 2
8em7 B 265 B 278
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 265 and 278.
Details
Redox score ?
88
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
265
Residue number B
278
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 265 of Low-density lipoprotein receptor-related protein 2
Cysteine 278 of Low-density lipoprotein receptor-related protein 2
2i1p A 1208 A 1223
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1208 and 1223.
Details
Redox score ?
87
PDB code
2i1p
Structure name
solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin
Structure deposition date
2006-08-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
40
Minimum pKa ?
nan
% buried
nan
Peptide accession
P98158
Residue number A
1208
Residue number B
1223
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1208 of Low-density lipoprotein receptor-related protein 2
Cysteine 1223 of Low-density lipoprotein receptor-related protein 2
8em4 B 1169 B 1184
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1169 and 1184.
Details
Redox score ?
87
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
40
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1169
Residue number B
1184
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1169 of Low-density lipoprotein receptor-related protein 2
Cysteine 1184 of Low-density lipoprotein receptor-related protein 2
8em7 B 1195 B 1214
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1195 and 1214.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1195
Residue number B
1214
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1195 of Low-density lipoprotein receptor-related protein 2
Cysteine 1214 of Low-density lipoprotein receptor-related protein 2
8em4 B 1395 B 1405
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1395 and 1405.
Details
Redox score ?
87
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1395
Residue number B
1405
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1395 of Low-density lipoprotein receptor-related protein 2
Cysteine 1405 of Low-density lipoprotein receptor-related protein 2
8em7 B 28 B 40
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 28 and 40.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
28
Residue number B
40
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 28 of Low-density lipoprotein receptor-related protein 2
Cysteine 40 of Low-density lipoprotein receptor-related protein 2
8em7 B 1291 B 1306
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1291 and 1306.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
1291
Residue number B
1306
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1291 of Low-density lipoprotein receptor-related protein 2
Cysteine 1306 of Low-density lipoprotein receptor-related protein 2
8em4 A 47 A 62
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 47 and 62.
Details
Redox score ?
87
PDB code
8em4
Structure name
cryo-em structure of lrp2 at ph 7
Structure deposition date
2022-09-26
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
47
Residue number B
62
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 47 of Low-density lipoprotein receptor-related protein 2
Cysteine 62 of Low-density lipoprotein receptor-related protein 2
8em7 A 2995 A 3007
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 2995 and 3007.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
44
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
2995
Residue number B
3007
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 2995 of Low-density lipoprotein receptor-related protein 2
Cysteine 3007 of Low-density lipoprotein receptor-related protein 2
8em7 B 3972 B 3981
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3972 and 3981.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3972
Residue number B
3981
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3972 of Low-density lipoprotein receptor-related protein 2
Cysteine 3981 of Low-density lipoprotein receptor-related protein 2
2m0p A 1128 A 1143
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 1128 and 1143.
Details
Redox score ?
87
PDB code
2m0p
Structure name
solution structure of the tenth complement type repeat of human megalin
Structure deposition date
2012-11-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
44
Minimum pKa ?
nan
% buried
nan
Peptide accession
P98164
Residue number A
1128
Residue number B
1143
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 1128 of Low-density lipoprotein receptor-related protein 2
Cysteine 1143 of Low-density lipoprotein receptor-related protein 2
8em7 B 222 B 234
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 222 and 234.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
222
Residue number B
234
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 222 of Low-density lipoprotein receptor-related protein 2
Cysteine 234 of Low-density lipoprotein receptor-related protein 2
8em7 A 3937 A 3955
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 3937 and 3955.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
3937
Residue number B
3955
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 3937 of Low-density lipoprotein receptor-related protein 2
Cysteine 3955 of Low-density lipoprotein receptor-related protein 2
8em7 A 202 A 217
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 202 and 217.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
43
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
202
Residue number B
217
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 202 of Low-density lipoprotein receptor-related protein 2
Cysteine 217 of Low-density lipoprotein receptor-related protein 2
8em7 B 2801 B 2818
A redox-regulated disulphide may form within Low-density lipoprotein receptor-related protein 2 between cysteines 2801 and 2818.
Details
Redox score ?
87
PDB code
8em7
Structure name
cryo-em structure of lrp2 at ph 5
Structure deposition date
2022-09-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
A2ARV4
Residue number A
2801
Residue number B
2818
Peptide name
Low-density lipoprotein receptor-related protein 2
Ligandability
Cysteine 2801 of Low-density lipoprotein receptor-related protein 2
Cysteine 2818 of Low-density lipoprotein receptor-related protein 2
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