Interleukin-5 receptor subunit alpha
Intramolecular
Cysteine 182 and cysteine 196
Cysteine 134 and cysteine 155
Cysteine 269 and cysteine 316
Cysteine 155 and cysteine 196
Cysteine 155 and cysteine 182
Cysteine 134 and cysteine 196
Cysteine 134 and cysteine 182
3va2 C 182 C 196
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 182 and 196.
Details
Redox score ?
87
PDB code
3va2
Structure name
crystal structure of human interleukin-5 in complex with its alpha receptor
Structure deposition date
2011-12-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
182
Residue number B
196
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 182 of Interleukin-5 receptor subunit alpha
Cysteine 196 of Interleukin-5 receptor subunit alpha
6h41 A 114 A 135
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 134 and 155 (114 and 135 respectively in this structure).
Details
Redox score ?
85
PDB code
6h41
Structure name
structure of the complex of the il-5 inhibitory peptide af17121 bound to the il-5 receptor il-5ralpha
Structure deposition date
2018-07-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
134
Residue number B
155
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 134 of Interleukin-5 receptor subunit alpha
Cysteine 155 of Interleukin-5 receptor subunit alpha
3va2 C 269 C 316
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 269 and 316.
Details
Redox score ?
82
PDB code
3va2
Structure name
crystal structure of human interleukin-5 in complex with its alpha receptor
Structure deposition date
2011-12-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
269
Residue number B
316
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 269 of Interleukin-5 receptor subunit alpha
Cysteine 316 of Interleukin-5 receptor subunit alpha
3qt2 B 135 B 176
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 155 and 196 (135 and 176 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
3qt2
Structure name
structure of a cytokine ligand-receptor complex
Structure deposition date
2011-02-22
Thiol separation (Å)
6
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
155
Residue number B
196
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 155 of Interleukin-5 receptor subunit alpha
Cysteine 196 of Interleukin-5 receptor subunit alpha
6h41 A 135 A 162
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 155 and 182 (135 and 162 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6h41
Structure name
structure of the complex of the il-5 inhibitory peptide af17121 bound to the il-5 receptor il-5ralpha
Structure deposition date
2018-07-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
155
Residue number B
182
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 155 of Interleukin-5 receptor subunit alpha
Cysteine 182 of Interleukin-5 receptor subunit alpha
6h41 A 114 A 176
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 134 and 196 (114 and 176 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6h41
Structure name
structure of the complex of the il-5 inhibitory peptide af17121 bound to the il-5 receptor il-5ralpha
Structure deposition date
2018-07-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
134
Residue number B
196
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 134 of Interleukin-5 receptor subunit alpha
Cysteine 196 of Interleukin-5 receptor subunit alpha
3qt2 B 114 B 162
A redox-regulated disulphide may form within Interleukin-5 receptor subunit alpha between cysteines 134 and 182 (114 and 162 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
3qt2
Structure name
structure of a cytokine ligand-receptor complex
Structure deposition date
2011-02-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q01344
Residue number A
134
Residue number B
182
Peptide name
Interleukin-5 receptor subunit alpha
Ligandability
Cysteine 134 of Interleukin-5 receptor subunit alpha
Cysteine 182 of Interleukin-5 receptor subunit alpha
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