Fatty acid-binding protein 5
Intermolecular
Cysteine 47 and cysteine 67 L
Intramolecular
Cysteine 67 and cysteine 87
Cysteine 120 and cysteine 127 L
Cysteine 43 and cysteine 67 L
Cysteine 47 and cysteine 87 L
4azr A 47 B 67
A redox-regulated disulphide may form between two units of Fatty acid-binding protein 5 at cysteines 47 and 67. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
4azr
Structure name
human epidermal fatty acid-binding protein (fabp5) in complex with the endocannabinoid anandamide
Structure deposition date
2012-06-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
8
% buried
36
Peptide A name
Fatty acid-binding protein 5
Peptide B name
Fatty acid-binding protein 5
Peptide A accession
Q01469
Peptide B accession
Q01469
Peptide A residue number
47
Peptide B residue number
67
Ligandability
Cysteine 47 of Fatty acid-binding protein 5
Cysteine 67 of Fatty acid-binding protein 5
1b56 A 67 A 87
A redox-regulated disulphide may form within Fatty acid-binding protein 5 between cysteines 67 and 87.
Details
Redox score ?
82
PDB code
1b56
Structure name
human recombinant epidermal fatty acid binding protein
Structure deposition date
1999-01-12
Thiol separation (Å)
3
Half-sphere exposure sum ?
65
Minimum pKa ?
8
% buried
62
Peptide accession
Q01469
Residue number A
67
Residue number B
87
Peptide name
Fatty acid-binding protein 5
Ligandability
Cysteine 67 of Fatty acid-binding protein 5
Cysteine 87 of Fatty acid-binding protein 5
4azr B 120 B 127
A redox-regulated disulphide may form within Fatty acid-binding protein 5 between cysteines 120 and 127.
Details
Redox score ?
71
PDB code
4azr
Structure name
human epidermal fatty acid-binding protein (fabp5) in complex with the endocannabinoid anandamide
Structure deposition date
2012-06-26
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
8
% buried
81
Peptide accession
Q01469
Residue number A
120
Residue number B
127
Peptide name
Fatty acid-binding protein 5
Ligandability
Cysteine 120 of Fatty acid-binding protein 5
Cysteine 127 of Fatty acid-binding protein 5
1jjj A 43 A 67
A redox-regulated disulphide may form within Fatty acid-binding protein 5 between cysteines 43 and 67. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1jjj
Structure name
solution structure of recombinant human epidermal-type fatty acid binding protein
Structure deposition date
2001-07-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
9
% buried
70
Peptide accession
Q01469
Residue number A
43
Residue number B
67
Peptide name
Fatty acid-binding protein 5
Ligandability
Cysteine 43 of Fatty acid-binding protein 5
Cysteine 67 of Fatty acid-binding protein 5
5ur9 D 47 D 87
A redox-regulated disulphide may form within Fatty acid-binding protein 5 between cysteines 47 and 87. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5ur9
Structure name
enantiomer-specific binding of the potent antinociceptive agent sbfi- 26 to anandamide transporters fabp5
Structure deposition date
2017-02-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
11
% buried
66
Peptide accession
Q01469
Residue number A
47
Residue number B
87
Peptide name
Fatty acid-binding protein 5
Ligandability
Cysteine 47 of Fatty acid-binding protein 5
Cysteine 87 of Fatty acid-binding protein 5
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