a tool for identifying drug-targetable redox-active disulphides

Exosome component 10

Intramolecular

Cysteine 554 and cysteine 555

A redox-regulated disulphide may form within Exosome component 10 between cysteines 554 and 555.

Details

Redox score ?

61

PDB code

Structure name

crystal structure of the human rrp6 catalytic domain with d313n mutation in the active site

Structure deposition date

2011-06-02

Thiol separation (Å)

6

Half-sphere exposure sum ?

58

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

554

Residue number B

555

Peptide name

Exosome component 10

Ligandability

Cysteine 554 of Exosome component 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 555 of Exosome component 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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