ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Myocyte-specific enhancer factor 2A

Intramolecular
Cysteine 39 and cysteine 41
A redox-regulated disulphide may form within Myocyte-specific enhancer factor 2A between cysteines 39 and 41. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
3p57
Structure name
crystal structure of the p300 taz2 domain bound to mef2 on dna
Structure deposition date
2010-10-08
Thiol separation (Å)
6
Half-sphere exposure sum ?
70
Minimum pKa ?
12
% buried
81
Peptide accession
Q02078
Residue number A
39
Residue number B
41
Peptide name
Myocyte-specific enhancer factor 2A

Ligandability

Cysteine 39 of Myocyte-specific enhancer factor 2A

Cysteine 41 of Myocyte-specific enhancer factor 2A

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