Urokinase plasminogen activator surface receptor
Intermolecular
Cysteine 46 and cysteine 98
Cysteine 98 and cysteine 25
Cysteine 93 and cysteine 25
Intramolecular
Cysteine 28 and cysteine 34
Cysteine 25 and cysteine 46
Cysteine 269 and cysteine 287
Cysteine 39 and cysteine 67
Cysteine 175 and cysteine 192
Cysteine 219 and cysteine 227
Cysteine 25 and cysteine 39
More...Cysteine 137 and cysteine 169
Cysteine 216 and cysteine 244
Cysteine 237 and cysteine 263
Cysteine 94 and cysteine 99
Cysteine 93 and cysteine 98
Cysteine 120 and cysteine 127
Cysteine 193 and cysteine 198
Cysteine 117 and cysteine 144
Cysteine 288 and cysteine 293
Cysteine 117 and cysteine 137
Cysteine 216 and cysteine 237
Cysteine 39 and cysteine 46
Cysteine 25 and cysteine 67
Cysteine 216 and cysteine 263
Cysteine 46 and cysteine 67
Cysteine 117 and cysteine 169
Cysteine 144 and cysteine 193
Cysteine 47 and cysteine 99
Cysteine 244 and cysteine 293
Cysteine 144 and cysteine 198
Cysteine 137 and cysteine 144
Cysteine 244 and cysteine 263
Cysteine 237 and cysteine 244
Cysteine 46 and cysteine 93
Cysteine 117 and cysteine 198
Cysteine 26 and cysteine 99
Cysteine 244 and cysteine 288
Cysteine 216 and cysteine 293
Cysteine 146 and cysteine 168
Cysteine 216 and cysteine 288
7e17 A 24 B 76
A redox-regulated disulphide may form between two units of Urokinase plasminogen activator surface receptor at cysteines 46 and 98 (24 and 76 respectively in this structure).
Details
Redox score ?
70
PDB code
7e17
Structure name
structure of dimeric upar
Structure deposition date
2021-02-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide A name
Urokinase plasminogen activator surface receptor
Peptide B name
Urokinase plasminogen activator surface receptor
Peptide A accession
Q03405
Peptide B accession
Q03405
Peptide A residue number
46
Peptide B residue number
98
Ligandability
Cysteine 46 of Urokinase plasminogen activator surface receptor
Cysteine 98 of Urokinase plasminogen activator surface receptor
7e17 A 76 B 3
A redox-regulated disulphide may form between two units of Urokinase plasminogen activator surface receptor at cysteines 98 and 25 (76 and 3 respectively in this structure).
Details
Redox score ?
64
PDB code
7e17
Structure name
structure of dimeric upar
Structure deposition date
2021-02-01
Thiol separation (Å)
5
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide A name
Urokinase plasminogen activator surface receptor
Peptide B name
Urokinase plasminogen activator surface receptor
Peptide A accession
Q03405
Peptide B accession
Q03405
Peptide A residue number
98
Peptide B residue number
25
Ligandability
Cysteine 98 of Urokinase plasminogen activator surface receptor
Cysteine 25 of Urokinase plasminogen activator surface receptor
7e17 A 71 B 3
A redox-regulated disulphide may form between two units of Urokinase plasminogen activator surface receptor at cysteines 93 and 25 (71 and 3 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7e17
Structure name
structure of dimeric upar
Structure deposition date
2021-02-01
Thiol separation (Å)
6
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide A name
Urokinase plasminogen activator surface receptor
Peptide B name
Urokinase plasminogen activator surface receptor
Peptide A accession
Q03405
Peptide B accession
Q03405
Peptide A residue number
93
Peptide B residue number
25
Ligandability
Cysteine 93 of Urokinase plasminogen activator surface receptor
Cysteine 25 of Urokinase plasminogen activator surface receptor
2i9b G 6 G 12
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 28 and 34 (6 and 12 respectively in this structure).
Details
Redox score ?
89
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
28
Residue number B
34
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 28 of Urokinase plasminogen activator surface receptor
Cysteine 34 of Urokinase plasminogen activator surface receptor
7v63 A 3 A 24
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 25 and 46 (3 and 24 respectively in this structure).
Details
Redox score ?
86
PDB code
7v63
Structure name
structure of dimeric upar at low ph
Structure deposition date
2021-08-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
25
Residue number B
46
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 25 of Urokinase plasminogen activator surface receptor
Cysteine 46 of Urokinase plasminogen activator surface receptor
3bt1 U 247 U 265
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 269 and 287 (247 and 265 respectively in this structure).
Details
Redox score ?
86
PDB code
3bt1
Structure name
structure of urokinase receptor, urokinase and vitronectin complex
Structure deposition date
2007-12-27
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
269
Residue number B
287
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 269 of Urokinase plasminogen activator surface receptor
Cysteine 287 of Urokinase plasminogen activator surface receptor
4k24 U 17 U 45
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 39 and 67 (17 and 45 respectively in this structure).
Details
Redox score ?
86
PDB code
4k24
Structure name
structure of anti-upar fab atn-658 in complex with upar
Structure deposition date
2013-04-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
39
Residue number B
67
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 39 of Urokinase plasminogen activator surface receptor
Cysteine 67 of Urokinase plasminogen activator surface receptor
2fd6 U 153 U 170
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 175 and 192 (153 and 170 respectively in this structure).
Details
Redox score ?
85
PDB code
2fd6
Structure name
structure of human urokinase plasminogen activator in complex with urokinase receptor and an anti-upar antibody at 1
Structure deposition date
2005-12-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
175
Residue number B
192
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 175 of Urokinase plasminogen activator surface receptor
Cysteine 192 of Urokinase plasminogen activator surface receptor
2i9b F 197 F 205
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 219 and 227 (197 and 205 respectively in this structure).
Details
Redox score ?
83
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
219
Residue number B
227
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 219 of Urokinase plasminogen activator surface receptor
Cysteine 227 of Urokinase plasminogen activator surface receptor
4qti U 3 U 17
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 25 and 39 (3 and 17 respectively in this structure).
Details
Redox score ?
82
PDB code
4qti
Structure name
crystal structure of human upar in complex with anti-upar fab 8b12
Structure deposition date
2014-07-08
Thiol separation (Å)
3
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
25
Residue number B
39
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 25 of Urokinase plasminogen activator surface receptor
Cysteine 39 of Urokinase plasminogen activator surface receptor
3u74 U 115 U 147
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 137 and 169 (115 and 147 respectively in this structure).
Details
Redox score ?
81
PDB code
3u74
Structure name
crystal structure of stabilized human upar mutant
Structure deposition date
2011-10-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
137
Residue number B
169
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 137 of Urokinase plasminogen activator surface receptor
Cysteine 169 of Urokinase plasminogen activator surface receptor
7v63 B 194 B 222
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 216 and 244 (194 and 222 respectively in this structure).
Details
Redox score ?
81
PDB code
7v63
Structure name
structure of dimeric upar at low ph
Structure deposition date
2021-08-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
216
Residue number B
244
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 216 of Urokinase plasminogen activator surface receptor
Cysteine 244 of Urokinase plasminogen activator surface receptor
3u74 U 215 U 241
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 237 and 263 (215 and 241 respectively in this structure).
Details
Redox score ?
80
PDB code
3u74
Structure name
crystal structure of stabilized human upar mutant
Structure deposition date
2011-10-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
91
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
237
Residue number B
263
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 237 of Urokinase plasminogen activator surface receptor
Cysteine 263 of Urokinase plasminogen activator surface receptor
3laq V 71 V 76
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 94 and 99 (71 and 76 respectively in this structure).
Details
Redox score ?
80
PDB code
3laq
Structure name
structure-based engineering of species selectivity in the upa-upar interaction
Structure deposition date
2010-01-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P35456
Residue number A
94
Residue number B
99
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 94 of Urokinase plasminogen activator surface receptor
Cysteine 99 of Urokinase plasminogen activator surface receptor
2i9b H 71 H 76
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 93 and 98 (71 and 76 respectively in this structure).
Details
Redox score ?
80
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
93
Residue number B
98
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 93 of Urokinase plasminogen activator surface receptor
Cysteine 98 of Urokinase plasminogen activator surface receptor
4k24 U 98 U 105
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 120 and 127 (98 and 105 respectively in this structure).
Details
Redox score ?
80
PDB code
4k24
Structure name
structure of anti-upar fab atn-658 in complex with upar
Structure deposition date
2013-04-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
120
Residue number B
127
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 120 of Urokinase plasminogen activator surface receptor
Cysteine 127 of Urokinase plasminogen activator surface receptor
4qti U 171 U 176
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 193 and 198 (171 and 176 respectively in this structure).
Details
Redox score ?
79
PDB code
4qti
Structure name
crystal structure of human upar in complex with anti-upar fab 8b12
Structure deposition date
2014-07-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
193
Residue number B
198
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 193 of Urokinase plasminogen activator surface receptor
Cysteine 198 of Urokinase plasminogen activator surface receptor
4qti U 95 U 122
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 117 and 144 (95 and 122 respectively in this structure).
Details
Redox score ?
79
PDB code
4qti
Structure name
crystal structure of human upar in complex with anti-upar fab 8b12
Structure deposition date
2014-07-08
Thiol separation (Å)
2
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
117
Residue number B
144
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 117 of Urokinase plasminogen activator surface receptor
Cysteine 144 of Urokinase plasminogen activator surface receptor
7v63 A 266 A 271
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 288 and 293 (266 and 271 respectively in this structure).
Details
Redox score ?
79
PDB code
7v63
Structure name
structure of dimeric upar at low ph
Structure deposition date
2021-08-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
288
Residue number B
293
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 288 of Urokinase plasminogen activator surface receptor
Cysteine 293 of Urokinase plasminogen activator surface receptor
2i9b E 95 E 115
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 117 and 137 (95 and 115 respectively in this structure).
Details
Redox score ?
77
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
117
Residue number B
137
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 117 of Urokinase plasminogen activator surface receptor
Cysteine 137 of Urokinase plasminogen activator surface receptor
2fd6 U 194 U 215
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 216 and 237 (194 and 215 respectively in this structure).
Details
Redox score ?
77
PDB code
2fd6
Structure name
structure of human urokinase plasminogen activator in complex with urokinase receptor and an anti-upar antibody at 1
Structure deposition date
2005-12-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
216
Residue number B
237
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 216 of Urokinase plasminogen activator surface receptor
Cysteine 237 of Urokinase plasminogen activator surface receptor
4k24 U 17 U 24
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 39 and 46 (17 and 24 respectively in this structure).
Details
Redox score ?
75
PDB code
4k24
Structure name
structure of anti-upar fab atn-658 in complex with upar
Structure deposition date
2013-04-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
39
Residue number B
46
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 39 of Urokinase plasminogen activator surface receptor
Cysteine 46 of Urokinase plasminogen activator surface receptor
4qti U 3 U 45
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 25 and 67 (3 and 45 respectively in this structure).
Details
Redox score ?
75
PDB code
4qti
Structure name
crystal structure of human upar in complex with anti-upar fab 8b12
Structure deposition date
2014-07-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
25
Residue number B
67
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 25 of Urokinase plasminogen activator surface receptor
Cysteine 67 of Urokinase plasminogen activator surface receptor
4k24 U 194 U 241
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 216 and 263 (194 and 241 respectively in this structure).
Details
Redox score ?
71
PDB code
4k24
Structure name
structure of anti-upar fab atn-658 in complex with upar
Structure deposition date
2013-04-08
Thiol separation (Å)
3
Half-sphere exposure sum ?
98
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
216
Residue number B
263
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 216 of Urokinase plasminogen activator surface receptor
Cysteine 263 of Urokinase plasminogen activator surface receptor
2i9b E 24 E 45
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 46 and 67 (24 and 45 respectively in this structure).
Details
Redox score ?
70
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
46
Residue number B
67
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 46 of Urokinase plasminogen activator surface receptor
Cysteine 67 of Urokinase plasminogen activator surface receptor
2i9b F 95 F 147
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 117 and 169 (95 and 147 respectively in this structure).
Details
Redox score ?
69
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
117
Residue number B
169
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 117 of Urokinase plasminogen activator surface receptor
Cysteine 169 of Urokinase plasminogen activator surface receptor
3u74 U 122 U 171
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 144 and 193 (122 and 171 respectively in this structure).
Details
Redox score ?
67
PDB code
3u74
Structure name
crystal structure of stabilized human upar mutant
Structure deposition date
2011-10-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
144
Residue number B
193
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 144 of Urokinase plasminogen activator surface receptor
Cysteine 193 of Urokinase plasminogen activator surface receptor
3laq U 24 U 76
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 47 and 99 (24 and 76 respectively in this structure).
Details
Redox score ?
66
PDB code
3laq
Structure name
structure-based engineering of species selectivity in the upa-upar interaction
Structure deposition date
2010-01-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P35456
Residue number A
47
Residue number B
99
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 47 of Urokinase plasminogen activator surface receptor
Cysteine 99 of Urokinase plasminogen activator surface receptor
3u73 U 222 U 271
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 244 and 293 (222 and 271 respectively in this structure).
Details
Redox score ?
65
PDB code
3u73
Structure name
crystal structure of stabilized human upar mutant in complex with atf
Structure deposition date
2011-10-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
244
Residue number B
293
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 244 of Urokinase plasminogen activator surface receptor
Cysteine 293 of Urokinase plasminogen activator surface receptor
3bt1 U 122 U 176
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 144 and 198 (122 and 176 respectively in this structure).
Details
Redox score ?
65
PDB code
3bt1
Structure name
structure of urokinase receptor, urokinase and vitronectin complex
Structure deposition date
2007-12-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
144
Residue number B
198
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 144 of Urokinase plasminogen activator surface receptor
Cysteine 198 of Urokinase plasminogen activator surface receptor
2i9b G 115 G 122
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 137 and 144 (115 and 122 respectively in this structure).
Details
Redox score ?
64
PDB code
2i9b
Structure name
crystal structure of atf-urokinase receptor complex
Structure deposition date
2006-09-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
137
Residue number B
144
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 137 of Urokinase plasminogen activator surface receptor
Cysteine 144 of Urokinase plasminogen activator surface receptor
4k24 U 222 U 241
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 244 and 263 (222 and 241 respectively in this structure).
Details
Redox score ?
64
PDB code
4k24
Structure name
structure of anti-upar fab atn-658 in complex with upar
Structure deposition date
2013-04-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
98
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
244
Residue number B
263
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 244 of Urokinase plasminogen activator surface receptor
Cysteine 263 of Urokinase plasminogen activator surface receptor
3bt2 U 215 U 222
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 237 and 244 (215 and 222 respectively in this structure).
Details
Redox score ?
62
PDB code
3bt2
Structure name
structure of urokinase receptor, urokinase and vitronectin complex
Structure deposition date
2007-12-27
Thiol separation (Å)
5
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
237
Residue number B
244
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 237 of Urokinase plasminogen activator surface receptor
Cysteine 244 of Urokinase plasminogen activator surface receptor
3u74 U 24 U 71
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 46 and 93 (24 and 71 respectively in this structure).
Details
Redox score ?
62
PDB code
3u74
Structure name
crystal structure of stabilized human upar mutant
Structure deposition date
2011-10-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
46
Residue number B
93
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 46 of Urokinase plasminogen activator surface receptor
Cysteine 93 of Urokinase plasminogen activator surface receptor
3u73 U 95 U 176
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 117 and 198 (95 and 176 respectively in this structure).
Details
Redox score ?
61
PDB code
3u73
Structure name
crystal structure of stabilized human upar mutant in complex with atf
Structure deposition date
2011-10-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
117
Residue number B
198
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 117 of Urokinase plasminogen activator surface receptor
Cysteine 198 of Urokinase plasminogen activator surface receptor
3laq V 3 V 76
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 26 and 99 (3 and 76 respectively in this structure).
Details
Redox score ?
61
PDB code
3laq
Structure name
structure-based engineering of species selectivity in the upa-upar interaction
Structure deposition date
2010-01-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P35456
Residue number A
26
Residue number B
99
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 26 of Urokinase plasminogen activator surface receptor
Cysteine 99 of Urokinase plasminogen activator surface receptor
2fd6 U 222 U 266
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 244 and 288 (222 and 266 respectively in this structure).
Details
Redox score ?
60
PDB code
2fd6
Structure name
structure of human urokinase plasminogen activator in complex with urokinase receptor and an anti-upar antibody at 1
Structure deposition date
2005-12-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
244
Residue number B
288
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 244 of Urokinase plasminogen activator surface receptor
Cysteine 288 of Urokinase plasminogen activator surface receptor
3bt1 U 194 U 271
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 216 and 293 (194 and 271 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
3bt1
Structure name
structure of urokinase receptor, urokinase and vitronectin complex
Structure deposition date
2007-12-27
Thiol separation (Å)
6
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
216
Residue number B
293
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 216 of Urokinase plasminogen activator surface receptor
Cysteine 293 of Urokinase plasminogen activator surface receptor
3laq U 123 U 145
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 146 and 168 (123 and 145 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
3laq
Structure name
structure-based engineering of species selectivity in the upa-upar interaction
Structure deposition date
2010-01-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
93
Minimum pKa ?
nan
% buried
nan
Peptide accession
P35456
Residue number A
146
Residue number B
168
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 146 of Urokinase plasminogen activator surface receptor
Cysteine 168 of Urokinase plasminogen activator surface receptor
3u74 U 194 U 266
A redox-regulated disulphide may form within Urokinase plasminogen activator surface receptor between cysteines 216 and 288 (194 and 266 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
3u74
Structure name
crystal structure of stabilized human upar mutant
Structure deposition date
2011-10-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q03405
Residue number A
216
Residue number B
288
Peptide name
Urokinase plasminogen activator surface receptor
Ligandability
Cysteine 216 of Urokinase plasminogen activator surface receptor
Cysteine 288 of Urokinase plasminogen activator surface receptor
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