a tool for identifying drug-targetable redox-active disulphides

Potassium voltage-gated channel subfamily C member 4

Intramolecular

Cysteine 6 and cysteine 24

A redox-regulated disulphide may form within Potassium voltage-gated channel subfamily C member 4 between cysteines 6 and 24.

Details

Redox score ?

85

PDB code

Structure name

control of k+ channel gating by protein phosphorylation: structural switches of the inactivation gate, nmr, 22 structures

Structure deposition date

1998-12-22

Thiol separation (Å)

3

Half-sphere exposure sum ?

18

Minimum pK_a ?

9

% buried

0

Peptide accession

Residue number A

6

Residue number B

24

Peptide name

Potassium voltage-gated channel subfamily C member 4

Ligandability

Cysteine 6 of Potassium voltage-gated channel subfamily C member 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 24 of Potassium voltage-gated channel subfamily C member 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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