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Neurogenic locus notch homolog protein 2

Intramolecular
Cysteine 503 and cysteine 518
Cysteine 465 and cysteine 480 L
Cysteine 427 and cysteine 442
Cysteine 520 and cysteine 529
Cysteine 1430 and cysteine 1443
Cysteine 444 and cysteine 453
Cysteine 482 and cysteine 491 L
Cysteine 1509 and cysteine 1522
Cysteine 498 and cysteine 509
Cysteine 419 and cysteine 433
More...
Cysteine 1472 and cysteine 1484
Cysteine 460 and cysteine 471
Cysteine 1466 and cysteine 1489
Cysteine 1480 and cysteine 1496
Cysteine 1503 and cysteine 1527
Cysteine 1518 and cysteine 1534
Cysteine 1632 and cysteine 1639 L
Cysteine 1425 and cysteine 1448
Cysteine 1439 and cysteine 1455
Cysteine 1466 and cysteine 1472
Cysteine 465 and cysteine 471
Cysteine 1503 and cysteine 1509
Cysteine 1430 and cysteine 1448
Cysteine 503 and cysteine 509
Cysteine 427 and cysteine 433
Cysteine 1472 and cysteine 1489
Cysteine 518 and cysteine 529
Cysteine 442 and cysteine 453
Cysteine 480 and cysteine 491 L
Cysteine 509 and cysteine 518
Cysteine 471 and cysteine 480 L
Cysteine 1509 and cysteine 1527
Cysteine 1466 and cysteine 1484
Cysteine 1443 and cysteine 1448
Cysteine 433 and cysteine 442
Cysteine 503 and cysteine 529
Cysteine 1503 and cysteine 1522
Cysteine 427 and cysteine 453
Cysteine 460 and cysteine 465
Cysteine 465 and cysteine 491
A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 503 and 518.

Details

Redox score ?
89
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
503
Residue number B
518
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 503 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 518 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 465 and 480.

Details

Redox score ?
88
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
465
Residue number B
480
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 465 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 480 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 427 and 442.

Details

Redox score ?
88
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
427
Residue number B
442
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 427 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 442 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 520 and 529.

Details

Redox score ?
88
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
520
Residue number B
529
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 520 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 529 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1430 and 1443.

Details

Redox score ?
88
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1430
Residue number B
1443
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1430 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1443 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 444 and 453.

Details

Redox score ?
88
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
444
Residue number B
453
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 444 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 453 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 482 and 491.

Details

Redox score ?
88
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
482
Residue number B
491
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 482 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 491 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1509 and 1522.

Details

Redox score ?
87
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1509
Residue number B
1522
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1509 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1522 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 498 and 509.

Details

Redox score ?
87
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
498
Residue number B
509
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 498 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 509 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 419 and 433.

Details

Redox score ?
87
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
419
Residue number B
433
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 419 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 433 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1472 and 1484.

Details

Redox score ?
87
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1472
Residue number B
1484
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1472 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1484 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 460 and 471.

Details

Redox score ?
87
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
460
Residue number B
471
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 460 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1466 and 1489.

Details

Redox score ?
86
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1466
Residue number B
1489
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1466 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1489 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1480 and 1496.

Details

Redox score ?
85
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
47
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1480
Residue number B
1496
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1480 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1496 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1503 and 1527.

Details

Redox score ?
85
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1503
Residue number B
1527
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1503 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1527 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1518 and 1534.

Details

Redox score ?
84
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1518
Residue number B
1534
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1518 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1534 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1632 and 1639.

Details

Redox score ?
83
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1632
Residue number B
1639
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1632 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 1639 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1425 and 1448.

Details

Redox score ?
81
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
nan
Peptide accession
Q04721
Residue number A
1425
Residue number B
1448
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1425 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1448 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1439 and 1455.

Details

Redox score ?
81
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1439
Residue number B
1455
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1439 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1455 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1466 and 1472.

Details

Redox score ?
80
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1466
Residue number B
1472
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1466 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1472 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 465 and 471.

Details

Redox score ?
78
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
465
Residue number B
471
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 465 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 471 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1503 and 1509.

Details

Redox score ?
77
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1503
Residue number B
1509
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1503 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1509 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1430 and 1448.

Details

Redox score ?
77
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1430
Residue number B
1448
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1430 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1448 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 503 and 509.

Details

Redox score ?
77
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
503
Residue number B
509
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 503 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 509 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 427 and 433.

Details

Redox score ?
74
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
427
Residue number B
433
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 427 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 433 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1472 and 1489.

Details

Redox score ?
73
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1472
Residue number B
1489
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1472 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1489 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 518 and 529.

Details

Redox score ?
72
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
518
Residue number B
529
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 518 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 529 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 442 and 453.

Details

Redox score ?
72
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
442
Residue number B
453
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 442 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 453 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 480 and 491.

Details

Redox score ?
72
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
480
Residue number B
491
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 480 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 491 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 509 and 518.

Details

Redox score ?
71
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
509
Residue number B
518
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 509 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 518 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 471 and 480.

Details

Redox score ?
70
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
471
Residue number B
480
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 471 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 480 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1509 and 1527.

Details

Redox score ?
70
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1509
Residue number B
1527
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1509 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1527 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1466 and 1484.

Details

Redox score ?
69
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1466
Residue number B
1484
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1466 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1484 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1443 and 1448.

Details

Redox score ?
69
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
5
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1443
Residue number B
1448
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1443 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1448 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 433 and 442.

Details

Redox score ?
68
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
433
Residue number B
442
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 433 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 442 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 503 and 529.

Details

Redox score ?
68
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
503
Residue number B
529
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 503 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 529 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 1503 and 1522.

Details

Redox score ?
68
PDB code
2oo4
Structure name
structure of lnr-hd (negative regulatory region) from human notch 2
Structure deposition date
2007-01-25
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
1503
Residue number B
1522
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 1503 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1522 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 427 and 453.

Details

Redox score ?
68
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
427
Residue number B
453
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 427 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 453 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 460 and 465.

Details

Redox score ?
66
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
460
Residue number B
465
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 460 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 465 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Neurogenic locus notch homolog protein 2 between cysteines 465 and 491.

Details

Redox score ?
66
PDB code
5mwb
Structure name
human notch-2 egf11-13
Structure deposition date
2017-01-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q04721
Residue number A
465
Residue number B
491
Peptide name
Neurogenic locus notch homolog protein 2

Ligandability

Cysteine 465 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 491 of Neurogenic locus notch homolog protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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