ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Serotransferrin

Intramolecular
Cysteine 358 and cysteine 615
Cysteine 156 and cysteine 350
Cysteine 493 and cysteine 684
Cysteine 582 and cysteine 596
Cysteine 190 and cysteine 196
Cysteine 374 and cysteine 387
Cysteine 514 and cysteine 525
Cysteine 421 and cysteine 693
Cysteine 38 and cysteine 58
Cysteine 246 and cysteine 260
More...
Cysteine 364 and cysteine 396
Cysteine 28 and cysteine 67
Cysteine 137 and cysteine 213
Cysteine 503 and cysteine 517
Cysteine 180 and cysteine 198
Cysteine 177 and cysteine 193
Cysteine 469 and cysteine 542
Cysteine 517 and cysteine 525
Cysteine 193 and cysteine 196
Cysteine 514 and cysteine 517
Cysteine 190 and cysteine 193
Cysteine 503 and cysteine 525
Cysteine 177 and cysteine 196
Cysteine 503 and cysteine 542
Cysteine 177 and cysteine 213
Cysteine 517 and cysteine 542
Cysteine 193 and cysteine 213
Cysteine 503 and cysteine 514
Cysteine 180 and cysteine 196
Cysteine 137 and cysteine 177
Cysteine 469 and cysteine 503
Cysteine 177 and cysteine 190
Cysteine 196 and cysteine 198
Cysteine 469 and cysteine 517
Cysteine 137 and cysteine 193
Cysteine 364 and cysteine 374
Cysteine 374 and cysteine 396
Cysteine 28 and cysteine 38
Cysteine 180 and cysteine 193
Cysteine 38 and cysteine 67
A redox-regulated disulphide may form within Serotransferrin between cysteines 358 and 615.

Details

Redox score ?
88
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
358
Residue number B
615
Peptide name
Serotransferrin

Ligandability

Cysteine 358 of Serotransferrin

Cysteine 615 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 156 and 350.

Details

Redox score ?
86
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
156
Residue number B
350
Peptide name
Serotransferrin

Ligandability

Cysteine 156 of Serotransferrin

Cysteine 350 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 493 and 684.

Details

Redox score ?
86
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
493
Residue number B
684
Peptide name
Serotransferrin

Ligandability

Cysteine 493 of Serotransferrin

Cysteine 684 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 582 and 596.

Details

Redox score ?
84
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
582
Residue number B
596
Peptide name
Serotransferrin

Ligandability

Cysteine 582 of Serotransferrin

Cysteine 596 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 190 and 196.

Details

Redox score ?
83
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
190
Residue number B
196
Peptide name
Serotransferrin

Ligandability

Cysteine 190 of Serotransferrin

Cysteine 196 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 374 and 387.

Details

Redox score ?
83
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
374
Residue number B
387
Peptide name
Serotransferrin

Ligandability

Cysteine 374 of Serotransferrin

Cysteine 387 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 514 and 525.

Details

Redox score ?
83
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
514
Residue number B
525
Peptide name
Serotransferrin

Ligandability

Cysteine 514 of Serotransferrin

Cysteine 525 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 421 and 693.

Details

Redox score ?
82
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
421
Residue number B
693
Peptide name
Serotransferrin

Ligandability

Cysteine 421 of Serotransferrin

Cysteine 693 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 38 and 58.

Details

Redox score ?
82
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
38
Residue number B
58
Peptide name
Serotransferrin

Ligandability

Cysteine 38 of Serotransferrin

Cysteine 58 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 246 and 260.

Details

Redox score ?
82
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
246
Residue number B
260
Peptide name
Serotransferrin

Ligandability

Cysteine 246 of Serotransferrin

Cysteine 260 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 364 and 396.

Details

Redox score ?
81
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
364
Residue number B
396
Peptide name
Serotransferrin

Ligandability

Cysteine 364 of Serotransferrin

Cysteine 396 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 28 and 67.

Details

Redox score ?
80
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
28
Residue number B
67
Peptide name
Serotransferrin

Ligandability

Cysteine 28 of Serotransferrin

Cysteine 67 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 137 and 213.

Details

Redox score ?
79
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
137
Residue number B
213
Peptide name
Serotransferrin

Ligandability

Cysteine 137 of Serotransferrin

Cysteine 213 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 503 and 517.

Details

Redox score ?
79
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
99
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
503
Residue number B
517
Peptide name
Serotransferrin

Ligandability

Cysteine 503 of Serotransferrin

Cysteine 517 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 180 and 198.

Details

Redox score ?
78
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
180
Residue number B
198
Peptide name
Serotransferrin

Ligandability

Cysteine 180 of Serotransferrin

Cysteine 198 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 177 and 193.

Details

Redox score ?
78
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
177
Residue number B
193
Peptide name
Serotransferrin

Ligandability

Cysteine 177 of Serotransferrin

Cysteine 193 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 469 and 542.

Details

Redox score ?
78
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
96
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
469
Residue number B
542
Peptide name
Serotransferrin

Ligandability

Cysteine 469 of Serotransferrin

Cysteine 542 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 517 and 525.

Details

Redox score ?
75
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
517
Residue number B
525
Peptide name
Serotransferrin

Ligandability

Cysteine 517 of Serotransferrin

Cysteine 525 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 193 and 196.

Details

Redox score ?
71
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
193
Residue number B
196
Peptide name
Serotransferrin

Ligandability

Cysteine 193 of Serotransferrin

Cysteine 196 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 514 and 517.

Details

Redox score ?
67
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
5
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
514
Residue number B
517
Peptide name
Serotransferrin

Ligandability

Cysteine 514 of Serotransferrin

Cysteine 517 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 190 and 193.

Details

Redox score ?
60
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
6
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
190
Residue number B
193
Peptide name
Serotransferrin

Ligandability

Cysteine 190 of Serotransferrin

Cysteine 193 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 503 and 525. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
5
Half-sphere exposure sum ?
94
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
503
Residue number B
525
Peptide name
Serotransferrin

Ligandability

Cysteine 503 of Serotransferrin

Cysteine 525 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 177 and 196. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
6
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
177
Residue number B
196
Peptide name
Serotransferrin

Ligandability

Cysteine 177 of Serotransferrin

Cysteine 196 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 503 and 542. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
5
Half-sphere exposure sum ?
98
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
503
Residue number B
542
Peptide name
Serotransferrin

Ligandability

Cysteine 503 of Serotransferrin

Cysteine 542 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 177 and 213. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
57
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
6
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
177
Residue number B
213
Peptide name
Serotransferrin

Ligandability

Cysteine 177 of Serotransferrin

Cysteine 213 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 517 and 542. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
55
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
517
Residue number B
542
Peptide name
Serotransferrin

Ligandability

Cysteine 517 of Serotransferrin

Cysteine 542 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 193 and 213. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
193
Residue number B
213
Peptide name
Serotransferrin

Ligandability

Cysteine 193 of Serotransferrin

Cysteine 213 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 503 and 514. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
93
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
503
Residue number B
514
Peptide name
Serotransferrin

Ligandability

Cysteine 503 of Serotransferrin

Cysteine 514 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 180 and 196. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
180
Residue number B
196
Peptide name
Serotransferrin

Ligandability

Cysteine 180 of Serotransferrin

Cysteine 196 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 137 and 177. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
103
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
137
Residue number B
177
Peptide name
Serotransferrin

Ligandability

Cysteine 137 of Serotransferrin

Cysteine 177 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 469 and 503. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
107
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
469
Residue number B
503
Peptide name
Serotransferrin

Ligandability

Cysteine 469 of Serotransferrin

Cysteine 503 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 177 and 190. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
92
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
177
Residue number B
190
Peptide name
Serotransferrin

Ligandability

Cysteine 177 of Serotransferrin

Cysteine 190 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 196 and 198. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
196
Residue number B
198
Peptide name
Serotransferrin

Ligandability

Cysteine 196 of Serotransferrin

Cysteine 198 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 469 and 517. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
98
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
469
Residue number B
517
Peptide name
Serotransferrin

Ligandability

Cysteine 469 of Serotransferrin

Cysteine 517 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 137 and 193. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
137
Residue number B
193
Peptide name
Serotransferrin

Ligandability

Cysteine 137 of Serotransferrin

Cysteine 193 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 364 and 374. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
364
Residue number B
374
Peptide name
Serotransferrin

Ligandability

Cysteine 364 of Serotransferrin

Cysteine 374 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 374 and 396. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
40
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
374
Residue number B
396
Peptide name
Serotransferrin

Ligandability

Cysteine 374 of Serotransferrin

Cysteine 396 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 28 and 38. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
28
Residue number B
38
Peptide name
Serotransferrin

Ligandability

Cysteine 28 of Serotransferrin

Cysteine 38 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 180 and 193. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
180
Residue number B
193
Peptide name
Serotransferrin

Ligandability

Cysteine 180 of Serotransferrin

Cysteine 193 of Serotransferrin

A redox-regulated disulphide may form within Serotransferrin between cysteines 38 and 67. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
36
PDB code
6uj6
Structure name
x-ray crystal structure of chromium-transferrin with synergistic anion malonate
Structure deposition date
2019-10-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q06AH7
Residue number A
38
Residue number B
67
Peptide name
Serotransferrin

Ligandability

Cysteine 38 of Serotransferrin

Cysteine 67 of Serotransferrin

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