ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Induced myeloid leukemia cell differentiation protein Mcl-1

Intermolecular
Cysteine 286 and cysteine 286
A redox-regulated disulphide may form between two units of Induced myeloid leukemia cell differentiation protein Mcl-1 at cysteines 286 and 286.

Details

Redox score ?
78
PDB code
3kz0
Structure name
mcl-1 complex with mcl-1-specific selected peptide
Structure deposition date
2009-12-07
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide A name
Induced myeloid leukemia cell differentiation protein Mcl-1
Peptide B name
Induced myeloid leukemia cell differentiation protein Mcl-1
Peptide A accession
Q07820
Peptide B accession
Q07820
Peptide A residue number
286
Peptide B residue number
286

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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