1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Intramolecular

A redox-regulated disulphide may form within 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial between cysteines 216 and 285. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3k9y

Structure name

crystal structure of rat mitochondrial p450 24a1 s57d in complex with cymal-5

Structure deposition date

2009-10-16

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q09128

Residue number A

216

Residue number B

285

Peptide name

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Ligandability

Cysteine 216 of 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.