a tool for identifying drug-targetable redox-active disulphides

ATP-dependent RNA helicase A

Intramolecular

Cysteine 552 and cysteine 558

A redox-regulated disulphide may form within ATP-dependent RNA helicase A between cysteines 552 and 558.

Details

Redox score ?

72

PDB code

Structure name

crystal structure analysis of a rna helicase

Structure deposition date

2010-01-29

Thiol separation (Å)

5

Half-sphere exposure sum ?

46

Minimum pK_a ?

10

% buried

36

Peptide accession

Residue number A

552

Residue number B

558

Peptide name

ATP-dependent RNA helicase A

Ligandability

Cysteine 552 of ATP-dependent RNA helicase A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 558 of ATP-dependent RNA helicase A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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