ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Fibrinogen-like protein 1

Intramolecular
Cysteine 248 and cysteine 261
Cysteine 83 and cysteine 112
A redox-regulated disulphide may form within Fibrinogen-like protein 1 between cysteines 248 and 261.

Details

Redox score ?
83
PDB code
7tz2
Structure name
structure of human fibrinogen-like protein 1
Structure deposition date
2022-02-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q08830
Residue number A
248
Residue number B
261
Peptide name
Fibrinogen-like protein 1

Ligandability

Cysteine 248 of Fibrinogen-like protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 261 of Fibrinogen-like protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Fibrinogen-like protein 1 between cysteines 83 and 112.

Details

Redox score ?
82
PDB code
7tz2
Structure name
structure of human fibrinogen-like protein 1
Structure deposition date
2022-02-15
Thiol separation (Å)
2
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q08830
Residue number A
83
Residue number B
112
Peptide name
Fibrinogen-like protein 1

Ligandability

Cysteine 83 of Fibrinogen-like protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 112 of Fibrinogen-like protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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