Myotonin-protein kinase

Intramolecular

A redox-regulated disulphide may form within Myotonin-protein kinase between cysteines 115 and 217. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2vd5

Structure name

structure of human myotonic dystrophy protein kinase in complex with the bisindoylmaleide inhibitor bim viii

Structure deposition date

2007-09-30

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q6P5Z6

Residue number A

115

Residue number B

217

Peptide name

Myotonin-protein kinase

Ligandability

Cysteine 115 of Myotonin-protein kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.