ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Nuclear cap-binding protein subunit 1

Intramolecular
Cysteine 456 and cysteine 477
A redox-regulated disulphide may form within Nuclear cap-binding protein subunit 1 between cysteines 456 and 477. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
1h2v
Structure name
structure of the human nuclear cap-binding-complex (cbc)
Structure deposition date
2002-08-16
Thiol separation (Å)
10
Half-sphere exposure sum ?
74
Minimum pKa ?
11
% buried
74
Peptide accession
Q09161
Residue number A
456
Residue number B
477
Peptide name
Nuclear cap-binding protein subunit 1

Ligandability

Cysteine 456 of Nuclear cap-binding protein subunit 1

Cysteine 477 of Nuclear cap-binding protein subunit 1

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