ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Ragulator complex protein LAMTOR4

Intermolecular
Cysteine 51 and cysteine 51 L
A redox-regulated disulphide may form between two units of Ragulator complex protein LAMTOR4 at cysteines 51 and 51. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
27
PDB code
5yk5
Structure name
structure of the human lamtor4-lamtor5 complex
Structure deposition date
2017-10-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
98
Minimum pKa ?
11
% buried
99
Peptide A name
Ragulator complex protein LAMTOR4
Peptide B name
Ragulator complex protein LAMTOR4
Peptide A accession
Q0VGL1
Peptide B accession
Q0VGL1
Peptide A residue number
51
Peptide B residue number
51

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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