a tool for identifying drug-targetable redox-active disulphides

Cadherin-17

Intramolecular

Cysteine 340 and cysteine 433

A redox-regulated disulphide may form within Cadherin-17 between cysteines 340 and 433.

Details

Redox score ?

86

PDB code

Structure name

crystal structure of li-cadherin ec1-4

Structure deposition date

2020-09-03

Thiol separation (Å)

2

Half-sphere exposure sum ?

60

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

340

Residue number B

433

Peptide name

Cadherin-17

Ligandability

Cysteine 340 of Cadherin-17

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 433 of Cadherin-17

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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