Tyrosine-protein kinase Mer

Intramolecular

A redox-regulated disulphide may form within Tyrosine-protein kinase Mer between cysteines 729 and 738. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2p0c

Structure name

catalytic domain of the proto-oncogene tyrosine-protein kinase mer

Structure deposition date

2007-02-28

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q12866

Residue number A

729

Residue number B

738

Peptide name

Tyrosine-protein kinase Mer

Ligandability

Cysteine 729 of Tyrosine-protein kinase Mer

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.