a tool for identifying drug-targetable redox-active disulphides

Vesicular integral-membrane protein VIP36

Intramolecular

Cysteine 202 and cysteine 239 L

A redox-regulated disulphide may form within Vesicular integral-membrane protein VIP36 between cysteines 202 and 239.

Details

Redox score ?

82

PDB code

Structure name

crystal structure of vip36 exoplasmic/lumenal domain, ca2+/man3glcnac- bound form

Structure deposition date

2007-01-04

Thiol separation (Å)

2

Half-sphere exposure sum ?

59

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

202

Residue number B

239

Peptide name

Vesicular integral-membrane protein VIP36

Ligandability

Cysteine 202 of Vesicular integral-membrane protein VIP36

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 239 of Vesicular integral-membrane protein VIP36

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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