Ral guanine nucleotide dissociation stimulator

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of Ral guanine nucleotide dissociation stimulator at cysteines 780 and 780 (16 and 16 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1lfd

Structure name

crystal structure of the active ras protein complexed with the ras- interacting domain of ralgds

Structure deposition date

1998-04-29

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Ral guanine nucleotide dissociation stimulator

Peptide B name

Ral guanine nucleotide dissociation stimulator

Peptide A accession

Q03386

Peptide B accession

Q03386

Peptide A residue number

780

Peptide B residue number

780

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Ral guanine nucleotide dissociation stimulator at cysteines 781 and 780 (17 and 16 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1lxd

Structure name

crystal structure of the ras interacting domain of ralgds, a guanine nucleotide dissociation stimulator of ral protein

Structure deposition date

1997-03-05

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

nan

Peptide A name

Ral guanine nucleotide dissociation stimulator

Peptide B name

Ral guanine nucleotide dissociation stimulator

Peptide A accession

Q03386

Peptide B accession

Q03386

Peptide A residue number

781

Peptide B residue number

780

Ligandability

Cysteine 781 of Ral guanine nucleotide dissociation stimulator

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 780 of Ral guanine nucleotide dissociation stimulator

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Ral guanine nucleotide dissociation stimulator between cysteines 799 and 800. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?