ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Cleavage stimulation factor subunit 3

Intramolecular
Cysteine 91 and cysteine 103
A redox-regulated disulphide may form within Cleavage stimulation factor subunit 3 between cysteines 91 and 103. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
38
PDB code
2ooe
Structure name
crystal structure of hat domain of murine cstf-77
Structure deposition date
2007-01-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
12
% buried
76
Peptide accession
Q99LI7
Residue number A
91
Residue number B
103
Peptide name
Cleavage stimulation factor subunit 3

Ligandability

Cysteine 91 of Cleavage stimulation factor subunit 3

Cysteine 103 of Cleavage stimulation factor subunit 3

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