Calcium-binding and coiled-coil domain-containing protein 2
Intramolecular
Cysteine 422 and cysteine 425
Cysteine 400 and cysteine 406
Cysteine 397 and cysteine 419
Cysteine 397 and cysteine 400
Cysteine 422 and cysteine 443
Cysteine 425 and cysteine 443
Cysteine 18 and cysteine 108
Cysteine 40 and cysteine 108
4xkl D 422 D 425
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 422 and 425.
Details
Redox score ?
85
PDB code
4xkl
Structure name
crystal structure of ndp52 zf2 in complex with mono-ubiquitin
Structure deposition date
2015-01-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
39
Minimum pKa ?
7
% buried
2
Peptide accession
Q13137
Residue number A
422
Residue number B
425
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 422 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 425 of Calcium-binding and coiled-coil domain-containing protein 2
5aaq A 400 A 406
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 400 and 406.
Details
Redox score ?
77
PDB code
5aaq
Structure name
tbk1 recruitment to cytosol-invading salmonella induces anti- bacterial autophagy
Structure deposition date
2015-07-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
21
Minimum pKa ?
9
% buried
0
Peptide accession
Q13137
Residue number A
400
Residue number B
406
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 400 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 406 of Calcium-binding and coiled-coil domain-containing protein 2
5aaq A 397 A 419
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 397 and 419.
Details
Redox score ?
70
PDB code
5aaq
Structure name
tbk1 recruitment to cytosol-invading salmonella induces anti- bacterial autophagy
Structure deposition date
2015-07-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
28
Minimum pKa ?
9
% buried
0
Peptide accession
Q13137
Residue number A
397
Residue number B
419
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 397 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 419 of Calcium-binding and coiled-coil domain-containing protein 2
5aaq A 397 A 400
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 397 and 400.
Details
Redox score ?
69
PDB code
5aaq
Structure name
tbk1 recruitment to cytosol-invading salmonella induces anti- bacterial autophagy
Structure deposition date
2015-07-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
21
Minimum pKa ?
9
% buried
0
Peptide accession
Q13137
Residue number A
397
Residue number B
400
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 397 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 400 of Calcium-binding and coiled-coil domain-containing protein 2
5aaq A 422 A 443
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 422 and 443. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
5aaq
Structure name
tbk1 recruitment to cytosol-invading salmonella induces anti- bacterial autophagy
Structure deposition date
2015-07-28
Thiol separation (Å)
10
Half-sphere exposure sum ?
34
Minimum pKa ?
7
% buried
0
Peptide accession
Q13137
Residue number A
422
Residue number B
443
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 422 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 443 of Calcium-binding and coiled-coil domain-containing protein 2
2mxp A 60 A 78
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 425 and 443 (60 and 78 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2mxp
Structure name
solution structure of ndp52 ubiquitin-binding zinc finger
Structure deposition date
2015-01-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
27
Minimum pKa ?
9
% buried
0
Peptide accession
Q13137
Residue number A
425
Residue number B
443
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 425 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 443 of Calcium-binding and coiled-coil domain-containing protein 2
7eaa B 18 B 108
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 18 and 108. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7eaa
Structure name
crystal structure of ndp52 skich domain in complex with rb1cc1 coiled- coil domain
Structure deposition date
2021-03-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
63
Peptide accession
Q13137
Residue number A
18
Residue number B
108
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 18 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 108 of Calcium-binding and coiled-coil domain-containing protein 2
7eaa B 40 B 108
A redox-regulated disulphide may form within Calcium-binding and coiled-coil domain-containing protein 2 between cysteines 40 and 108. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
25
PDB code
7eaa
Structure name
crystal structure of ndp52 skich domain in complex with rb1cc1 coiled- coil domain
Structure deposition date
2021-03-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
13
% buried
100
Peptide accession
Q13137
Residue number A
40
Residue number B
108
Peptide name
Calcium-binding and coiled-coil domain-containing protein 2
Ligandability
Cysteine 40 of Calcium-binding and coiled-coil domain-containing protein 2
Cysteine 108 of Calcium-binding and coiled-coil domain-containing protein 2
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