TAR DNA-binding protein 43

Intramolecular

A redox-regulated disulphide may form within TAR DNA-binding protein 43 between cysteines 173 and 175. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4iuf

Structure name

crystal structure of human tdp-43 rrm1 domain in complex with a single-stranded dna

Structure deposition date

2013-01-21

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q13148

Residue number A

173

Residue number B

175

Peptide name

TAR DNA-binding protein 43

Ligandability

Cysteine 173 of TAR DNA-binding protein 43

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.