cGMP-dependent protein kinase 2
5c6c A 240 B 240
A redox-regulated disulphide may form between two units of cGMP-dependent protein kinase 2 at cysteines 240 and 240.
Details
Redox score ?
69
PDB code
5c6c
Structure name
pkg ii's amino terminal cyclic nucleotide binding domain (cnb-a) in a complex with camp
Structure deposition date
2015-06-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
10
% buried
41
Peptide A name
cGMP-dependent protein kinase 2
Peptide B name
cGMP-dependent protein kinase 2
Peptide A accession
Q13237
Peptide B accession
Q13237
Peptide A residue number
240
Peptide B residue number
240
Ligandability
5c8w A 183 C 183
A redox-regulated disulphide may form between two units of cGMP-dependent protein kinase 2 at cysteines 183 and 183. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
5c8w
Structure name
pkg ii's amino terminal cyclic nucleotide binding domain (cnb-a) in a complex with cgmp
Structure deposition date
2015-06-26
Thiol separation (Å)
6
Half-sphere exposure sum ?
76
Minimum pKa ?
13
% buried
100
Peptide A name
cGMP-dependent protein kinase 2
Peptide B name
cGMP-dependent protein kinase 2
Peptide A accession
Q13237
Peptide B accession
Q13237
Peptide A residue number
183
Peptide B residue number
183
Ligandability
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