Noggin
Intramolecular
Cysteine 207 and cysteine 215
Cysteine 155 and cysteine 192
Cysteine 184 and cysteine 230
Cysteine 178 and cysteine 228
Cysteine 155 and cysteine 184
Cysteine 184 and cysteine 192
Cysteine 155 and cysteine 230
Cysteine 192 and cysteine 230
Cysteine 155 and cysteine 228
Cysteine 178 and cysteine 192
More...Cysteine 192 and cysteine 228
Cysteine 230 and cysteine 232
Cysteine 155 and cysteine 178
Cysteine 184 and cysteine 232
Cysteine 178 and cysteine 184
Cysteine 184 and cysteine 228
7ag0 A 207 A 215
A redox-regulated disulphide may form within Noggin between cysteines 207 and 215.
Details
Redox score ?
89
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
37
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
207
Residue number B
215
Peptide name
Noggin
Ligandability
Cysteine 207 of Noggin
Cysteine 215 of Noggin
7ag0 A 155 A 192
A redox-regulated disulphide may form within Noggin between cysteines 155 and 192.
Details
Redox score ?
88
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
155
Residue number B
192
Peptide name
Noggin
Ligandability
Cysteine 155 of Noggin
Cysteine 192 of Noggin
7ag0 A 184 A 230
A redox-regulated disulphide may form within Noggin between cysteines 184 and 230.
Details
Redox score ?
87
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
184
Residue number B
230
Peptide name
Noggin
Ligandability
Cysteine 184 of Noggin
Cysteine 230 of Noggin
7ag0 A 178 A 228
A redox-regulated disulphide may form within Noggin between cysteines 178 and 228.
Details
Redox score ?
85
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
178
Residue number B
228
Peptide name
Noggin
Ligandability
Cysteine 178 of Noggin
Cysteine 228 of Noggin
7ag0 A 155 A 184
A redox-regulated disulphide may form within Noggin between cysteines 155 and 184.
Details
Redox score ?
77
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
155
Residue number B
184
Peptide name
Noggin
Ligandability
Cysteine 155 of Noggin
Cysteine 184 of Noggin
7ag0 A 184 A 192
A redox-regulated disulphide may form within Noggin between cysteines 184 and 192.
Details
Redox score ?
74
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
184
Residue number B
192
Peptide name
Noggin
Ligandability
Cysteine 184 of Noggin
Cysteine 192 of Noggin
7ag0 A 155 A 230
A redox-regulated disulphide may form within Noggin between cysteines 155 and 230.
Details
Redox score ?
73
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
155
Residue number B
230
Peptide name
Noggin
Ligandability
Cysteine 155 of Noggin
Cysteine 230 of Noggin
1m4u A 192 A 230
A redox-regulated disulphide may form within Noggin between cysteines 192 and 230.
Details
Redox score ?
66
PDB code
1m4u
Structure name
crystal structure of bone morphogenetic protein-7 (bmp-7) in complex with the secreted antagonist noggin
Structure deposition date
2002-07-03
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
192
Residue number B
230
Peptide name
Noggin
Ligandability
Cysteine 192 of Noggin
Cysteine 230 of Noggin
7ag0 A 155 A 228
A redox-regulated disulphide may form within Noggin between cysteines 155 and 228.
Details
Redox score ?
62
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
155
Residue number B
228
Peptide name
Noggin
Ligandability
Cysteine 155 of Noggin
Cysteine 228 of Noggin
7ag0 A 178 A 192
A redox-regulated disulphide may form within Noggin between cysteines 178 and 192.
Details
Redox score ?
61
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
178
Residue number B
192
Peptide name
Noggin
Ligandability
Cysteine 178 of Noggin
Cysteine 192 of Noggin
7ag0 A 192 A 228
A redox-regulated disulphide may form within Noggin between cysteines 192 and 228.
Details
Redox score ?
61
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
6
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
192
Residue number B
228
Peptide name
Noggin
Ligandability
Cysteine 192 of Noggin
Cysteine 228 of Noggin
1m4u A 230 A 232
A redox-regulated disulphide may form within Noggin between cysteines 230 and 232. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
1m4u
Structure name
crystal structure of bone morphogenetic protein-7 (bmp-7) in complex with the secreted antagonist noggin
Structure deposition date
2002-07-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
nan
Peptide accession
Q13253
Residue number A
230
Residue number B
232
Peptide name
Noggin
Ligandability
Cysteine 230 of Noggin
Cysteine 232 of Noggin
1m4u A 155 A 178
A redox-regulated disulphide may form within Noggin between cysteines 155 and 178. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
1m4u
Structure name
crystal structure of bone morphogenetic protein-7 (bmp-7) in complex with the secreted antagonist noggin
Structure deposition date
2002-07-03
Thiol separation (Å)
7
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
155
Residue number B
178
Peptide name
Noggin
Ligandability
Cysteine 155 of Noggin
Cysteine 178 of Noggin
1m4u A 184 A 232
A redox-regulated disulphide may form within Noggin between cysteines 184 and 232. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
1m4u
Structure name
crystal structure of bone morphogenetic protein-7 (bmp-7) in complex with the secreted antagonist noggin
Structure deposition date
2002-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
nan
Peptide accession
Q13253
Residue number A
184
Residue number B
232
Peptide name
Noggin
Ligandability
Cysteine 184 of Noggin
Cysteine 232 of Noggin
7ag0 A 178 A 184
A redox-regulated disulphide may form within Noggin between cysteines 178 and 184. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
178
Residue number B
184
Peptide name
Noggin
Ligandability
Cysteine 178 of Noggin
Cysteine 184 of Noggin
7ag0 A 184 A 228
A redox-regulated disulphide may form within Noggin between cysteines 184 and 228. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
7ag0
Structure name
complex between the bone morphogenetic protein 2 and its antagonist noggin
Structure deposition date
2020-09-21
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13253
Residue number A
184
Residue number B
228
Peptide name
Noggin
Ligandability
Cysteine 184 of Noggin
Cysteine 228 of Noggin
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