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Transcription intermediary factor 1-beta

Intramolecular
Cysteine 83 and cysteine 117 L
Cysteine 640 and cysteine 643
Cysteine 117 and cysteine 120 L
Cysteine 640 and cysteine 669
Cysteine 640 and cysteine 666
Cysteine 65 and cysteine 91
Cysteine 65 and cysteine 68
Cysteine 154 and cysteine 157 L
Cysteine 643 and cysteine 669
Cysteine 628 and cysteine 651 L
More...
Cysteine 628 and cysteine 631 L
Cysteine 65 and cysteine 88
Cysteine 666 and cysteine 669
Cysteine 154 and cysteine 178 L
Cysteine 157 and cysteine 178 L
Cysteine 154 and cysteine 175 L
Cysteine 209 and cysteine 229 L
Cysteine 229 and cysteine 232 L
Cysteine 157 and cysteine 175
Cysteine 88 and cysteine 91
Cysteine 221 and cysteine 224
Cysteine 68 and cysteine 91
Cysteine 167 and cysteine 170 L
Cysteine 209 and cysteine 232 L
Cysteine 175 and cysteine 178 L
Cysteine 117 and cysteine 124 L
Cysteine 68 and cysteine 88
Cysteine 643 and cysteine 666
Cysteine 83 and cysteine 120 L
Cysteine 631 and cysteine 651
Cysteine 628 and cysteine 646 L
Cysteine 640 and cysteine 646
Cysteine 153 and cysteine 154 L
Cysteine 83 and cysteine 124
Cysteine 640 and cysteine 713
Cysteine 221 and cysteine 232 L
Cysteine 153 and cysteine 157
Cysteine 65 and cysteine 117 L
Cysteine 666 and cysteine 713
Cysteine 646 and cysteine 669
A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 83 and 117.

Details

Redox score ?
92
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
67
Minimum pKa ?
2
% buried
54
Peptide accession
Q13263
Residue number A
83
Residue number B
117
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 83 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 117 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 640 and 643.

Details

Redox score ?
91
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
1
% buried
54
Peptide accession
Q13263
Residue number A
640
Residue number B
643
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 640 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 643 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 117 and 120.

Details

Redox score ?
91
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
2
% buried
42
Peptide accession
Q13263
Residue number A
117
Residue number B
120
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 117 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 120 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 640 and 669 (40 and 69 respectively in this structure).

Details

Redox score ?
89
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
6
% buried
6
Peptide accession
Q13263
Residue number A
640
Residue number B
669
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 640 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 669 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 640 and 666.

Details

Redox score ?
89
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
82
Minimum pKa ?
1
% buried
75
Peptide accession
Q13263
Residue number A
640
Residue number B
666
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 640 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 666 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 65 and 91.

Details

Redox score ?
87
PDB code
6h3a
Structure name
crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain
Structure deposition date
2018-07-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
6
% buried
21
Peptide accession
Q13263
Residue number A
65
Residue number B
91
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 65 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 91 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 65 and 68.

Details

Redox score ?
86
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
60
Minimum pKa ?
6
% buried
30
Peptide accession
Q13263
Residue number A
65
Residue number B
68
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 65 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 68 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 154 and 157.

Details

Redox score ?
86
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
6
% buried
12
Peptide accession
Q62318
Residue number A
154
Residue number B
157
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 154 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 157 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 643 and 669 (43 and 69 respectively in this structure).

Details

Redox score ?
86
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
8
% buried
0
Peptide accession
Q13263
Residue number A
643
Residue number B
669
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 643 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 669 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 628 and 651 (28 and 51 respectively in this structure).

Details

Redox score ?
86
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
7
% buried
10
Peptide accession
Q13263
Residue number A
628
Residue number B
651
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 628 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 651 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 628 and 631 (28 and 31 respectively in this structure).

Details

Redox score ?
85
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
7
% buried
4
Peptide accession
Q13263
Residue number A
628
Residue number B
631
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 628 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 631 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 65 and 88.

Details

Redox score ?
85
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
71
Minimum pKa ?
6
% buried
33
Peptide accession
Q13263
Residue number A
65
Residue number B
88
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 65 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 88 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 666 and 669 (66 and 69 respectively in this structure).

Details

Redox score ?
84
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
0
Peptide accession
Q13263
Residue number A
666
Residue number B
669
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 666 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 669 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 154 and 178.

Details

Redox score ?
84
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
6
% buried
31
Peptide accession
Q62318
Residue number A
154
Residue number B
178
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 154 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 178 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 157 and 178.

Details

Redox score ?
84
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
6
% buried
15
Peptide accession
Q62318
Residue number A
157
Residue number B
178
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 157 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 178 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 154 and 175.

Details

Redox score ?
83
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
18
Peptide accession
Q62318
Residue number A
154
Residue number B
175
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 154 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 175 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 209 and 229.

Details

Redox score ?
83
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
54
Minimum pKa ?
8
% buried
nan
Peptide accession
Q13263
Residue number A
209
Residue number B
229
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 209 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 229 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 229 and 232.

Details

Redox score ?
83
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
6
Peptide accession
Q13263
Residue number A
229
Residue number B
232
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 229 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 232 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 157 and 175.

Details

Redox score ?
83
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
3
Peptide accession
Q62318
Residue number A
157
Residue number B
175
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 157 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 175 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 88 and 91.

Details

Redox score ?
82
PDB code
6h3a
Structure name
crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain
Structure deposition date
2018-07-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
6
% buried
11
Peptide accession
Q13263
Residue number A
88
Residue number B
91
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 88 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 91 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 221 and 224.

Details

Redox score ?
82
PDB code
6qu1
Structure name
crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain at 3
Structure deposition date
2019-02-26
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
7
% buried
0
Peptide accession
Q13263
Residue number A
221
Residue number B
224
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 221 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 224 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 68 and 91.

Details

Redox score ?
82
PDB code
6h3a
Structure name
crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain
Structure deposition date
2018-07-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
6
% buried
6
Peptide accession
Q13263
Residue number A
68
Residue number B
91
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 68 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 91 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 167 and 170.

Details

Redox score ?
80
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
8
% buried
21
Peptide accession
Q62318
Residue number A
167
Residue number B
170
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 167 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 170 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 209 and 232.

Details

Redox score ?
80
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
nan
Peptide accession
Q13263
Residue number A
209
Residue number B
232
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 209 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 232 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 175 and 178.

Details

Redox score ?
77
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
8
% buried
18
Peptide accession
Q62318
Residue number A
175
Residue number B
178
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 175 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 178 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 117 and 124.

Details

Redox score ?
75
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
54
Minimum pKa ?
2
% buried
40
Peptide accession
Q13263
Residue number A
117
Residue number B
124
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 117 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 124 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 68 and 88.

Details

Redox score ?
72
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
10
% buried
22
Peptide accession
Q13263
Residue number A
68
Residue number B
88
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 68 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 88 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 643 and 666.

Details

Redox score ?
71
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
76
Minimum pKa ?
9
% buried
72
Peptide accession
Q13263
Residue number A
643
Residue number B
666
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 643 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 666 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 83 and 120.

Details

Redox score ?
71
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
9
% buried
50
Peptide accession
Q13263
Residue number A
83
Residue number B
120
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 83 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 120 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 631 and 651.

Details

Redox score ?
70
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
8
% buried
52
Peptide accession
Q13263
Residue number A
631
Residue number B
651
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 631 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 651 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 628 and 646 (28 and 46 respectively in this structure).

Details

Redox score ?
66
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
64
Minimum pKa ?
7
% buried
11
Peptide accession
Q13263
Residue number A
628
Residue number B
646
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 628 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 646 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 640 and 646.

Details

Redox score ?
61
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
78
Minimum pKa ?
1
% buried
46
Peptide accession
Q13263
Residue number A
640
Residue number B
646
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 640 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 646 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 153 and 154. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
46
Minimum pKa ?
6
% buried
10
Peptide accession
Q62318
Residue number A
153
Residue number B
154
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 153 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 154 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 83 and 124. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
58
PDB code
6qaj
Structure name
structure of the tripartite motif of kap1/trim28
Structure deposition date
2018-12-19
Thiol separation (Å)
6
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
44
Peptide accession
Q13263
Residue number A
83
Residue number B
124
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 83 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 124 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 640 and 713. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
1
% buried
78
Peptide accession
Q13263
Residue number A
640
Residue number B
713
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 640 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 713 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 221 and 232. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
53
PDB code
6qu1
Structure name
crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain at 3
Structure deposition date
2019-02-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
56
Minimum pKa ?
7
% buried
0
Peptide accession
Q13263
Residue number A
221
Residue number B
232
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 221 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 232 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 153 and 157. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
6o5k
Structure name
murine trim28 bbox1 domain
Structure deposition date
2019-03-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
2
Peptide accession
Q62318
Residue number A
153
Residue number B
157
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 153 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 157 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 65 and 117. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
6i9h
Structure name
solution structure of trim28 ring domain
Structure deposition date
2018-11-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
7
% buried
38
Peptide accession
Q13263
Residue number A
65
Residue number B
117
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 65 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 117 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 666 and 713. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
2ro1
Structure name
nmr solution structures of human kap1 phd finger-bromodomain
Structure deposition date
2008-03-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
92
Minimum pKa ?
12
% buried
96
Peptide accession
Q13263
Residue number A
666
Residue number B
713
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 666 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 713 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Transcription intermediary factor 1-beta between cysteines 646 and 669 (46 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
51
PDB code
1fp0
Structure name
solution structure of the phd domain from the kap-1 corepressor
Structure deposition date
2000-08-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
6
Peptide accession
Q13263
Residue number A
646
Residue number B
669
Peptide name
Transcription intermediary factor 1-beta

Ligandability

Cysteine 646 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 669 of Transcription intermediary factor 1-beta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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