Serine-protein kinase ATM
Intramolecular
Cysteine 1873 and cysteine 1900
Cysteine 633 and cysteine 790
Cysteine 1899 and cysteine 1900
Cysteine 1831 and cysteine 1838
Cysteine 1821 and cysteine 1900
Cysteine 2286 and cysteine 2323
Cysteine 1821 and cysteine 1899
Cysteine 1873 and cysteine 1899
Cysteine 1838 and cysteine 1873
Cysteine 536 and cysteine 540
More...Cysteine 1900 and cysteine 1948
Cysteine 1811 and cysteine 1831
Cysteine 783 and cysteine 786
Cysteine 198 and cysteine 199
Cysteine 11 and cysteine 12
Cysteine 1811 and cysteine 1838
Cysteine 1873 and cysteine 1948
Cysteine 2930 and cysteine 2931
Cysteine 977 and cysteine 987
Cysteine 2753 and cysteine 2770
Cysteine 1494 and cysteine 1495
Cysteine 2801 and cysteine 2824
Cysteine 1736 and cysteine 1831
Cysteine 1164 and cysteine 1168
Cysteine 1482 and cysteine 1495
Cysteine 540 and cysteine 541
Cysteine 532 and cysteine 541 L
Cysteine 783 and cysteine 907
Cysteine 2337 and cysteine 2341
Cysteine 819 and cysteine 905
Cysteine 728 and cysteine 730
Cysteine 786 and cysteine 907
Cysteine 977 and cysteine 1045
Cysteine 157 and cysteine 987
Cysteine 905 and cysteine 907
7sic A 1873 A 1900
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1873 and 1900.
Details
Redox score ?
84
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
7
% buried
62
Peptide accession
Q13315
Residue number A
1873
Residue number B
1900
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1873 of Serine-protein kinase ATM
Cysteine 1900 of Serine-protein kinase ATM
7sic B 633 B 790
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 633 and 790.
Details
Redox score ?
82
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
7
% buried
0
Peptide accession
Q13315
Residue number A
633
Residue number B
790
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 633 of Serine-protein kinase ATM
Cysteine 790 of Serine-protein kinase ATM
7ni4 A 1899 A 1900
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1899 and 1900.
Details
Redox score ?
78
PDB code
7ni4
Structure name
human atm kinase domain with bound m4076 inhibitor
Structure deposition date
2021-02-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
8
% buried
0
Peptide accession
Q13315
Residue number A
1899
Residue number B
1900
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1899 of Serine-protein kinase ATM
Cysteine 1900 of Serine-protein kinase ATM
7ni4 A 1831 A 1838
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1831 and 1838.
Details
Redox score ?
74
PDB code
7ni4
Structure name
human atm kinase domain with bound m4076 inhibitor
Structure deposition date
2021-02-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
7
% buried
77
Peptide accession
Q13315
Residue number A
1831
Residue number B
1838
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1831 of Serine-protein kinase ATM
Cysteine 1838 of Serine-protein kinase ATM
6k9k A 1821 A 1900
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1821 and 1900.
Details
Redox score ?
65
PDB code
6k9k
Structure name
monomeric human atm (ataxia telangiectasia mutated) kinase
Structure deposition date
2019-06-16
Thiol separation (Å)
6
Half-sphere exposure sum ?
38
Minimum pKa ?
9
% buried
0
Peptide accession
Q13315
Residue number A
1821
Residue number B
1900
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1821 of Serine-protein kinase ATM
Cysteine 1900 of Serine-protein kinase ATM
7ni6 B 2286 B 2323
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 2286 and 2323.
Details
Redox score ?
61
PDB code
7ni6
Structure name
human atm kinase with bound atpys
Structure deposition date
2021-02-11
Thiol separation (Å)
7
Half-sphere exposure sum ?
38
Minimum pKa ?
9
% buried
0
Peptide accession
Q13315
Residue number A
2286
Residue number B
2323
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 2286 of Serine-protein kinase ATM
Cysteine 2323 of Serine-protein kinase ATM
6k9k A 1821 A 1899
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1821 and 1899.
Details
Redox score ?
61
PDB code
6k9k
Structure name
monomeric human atm (ataxia telangiectasia mutated) kinase
Structure deposition date
2019-06-16
Thiol separation (Å)
7
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
12
Peptide accession
Q13315
Residue number A
1821
Residue number B
1899
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1821 of Serine-protein kinase ATM
Cysteine 1899 of Serine-protein kinase ATM
7sic B 1873 B 1899
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1873 and 1899. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
36
Peptide accession
Q13315
Residue number A
1873
Residue number B
1899
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1873 of Serine-protein kinase ATM
Cysteine 1899 of Serine-protein kinase ATM
6k9k A 1838 A 1873
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1838 and 1873. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
6k9k
Structure name
monomeric human atm (ataxia telangiectasia mutated) kinase
Structure deposition date
2019-06-16
Thiol separation (Å)
7
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
54
Peptide accession
Q13315
Residue number A
1838
Residue number B
1873
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1838 of Serine-protein kinase ATM
Cysteine 1873 of Serine-protein kinase ATM
7ni5 A 536 A 540
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 536 and 540. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
56
Minimum pKa ?
10
% buried
34
Peptide accession
Q13315
Residue number A
536
Residue number B
540
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 536 of Serine-protein kinase ATM
Cysteine 540 of Serine-protein kinase ATM
7sic A 1900 A 1948
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1900 and 1948. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
7
% buried
54
Peptide accession
Q13315
Residue number A
1900
Residue number B
1948
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1900 of Serine-protein kinase ATM
Cysteine 1948 of Serine-protein kinase ATM
7sid C 1811 C 1831
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1811 and 1831. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7sid
Structure name
human atm dimer bound to nbs1
Structure deposition date
2021-10-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
68
Minimum pKa ?
10
% buried
61
Peptide accession
Q13315
Residue number A
1811
Residue number B
1831
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1811 of Serine-protein kinase ATM
Cysteine 1831 of Serine-protein kinase ATM
7ni5 B 783 B 786
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 783 and 786. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
79
Minimum pKa ?
12
% buried
100
Peptide accession
Q13315
Residue number A
783
Residue number B
786
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 783 of Serine-protein kinase ATM
Cysteine 786 of Serine-protein kinase ATM
7sid A 198 A 199
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 198 and 199. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7sid
Structure name
human atm dimer bound to nbs1
Structure deposition date
2021-10-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
72
Minimum pKa ?
11
% buried
88
Peptide accession
Q13315
Residue number A
198
Residue number B
199
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 198 of Serine-protein kinase ATM
Cysteine 199 of Serine-protein kinase ATM
7ni5 B 11 B 12
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 11 and 12. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
7
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
60
Peptide accession
Q13315
Residue number A
11
Residue number B
12
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 11 of Serine-protein kinase ATM
Cysteine 12 of Serine-protein kinase ATM
7ni4 A 1811 A 1838
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1811 and 1838. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7ni4
Structure name
human atm kinase domain with bound m4076 inhibitor
Structure deposition date
2021-02-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
72
Minimum pKa ?
7
% buried
52
Peptide accession
Q13315
Residue number A
1811
Residue number B
1838
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1811 of Serine-protein kinase ATM
Cysteine 1838 of Serine-protein kinase ATM
7ni5 A 1873 A 1948
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1873 and 1948. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
70
Minimum pKa ?
10
% buried
70
Peptide accession
Q13315
Residue number A
1873
Residue number B
1948
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1873 of Serine-protein kinase ATM
Cysteine 1948 of Serine-protein kinase ATM
6k9l A 2930 A 2931
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 2930 and 2931. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6k9l
Structure name
4
Structure deposition date
2019-06-16
Thiol separation (Å)
7
Half-sphere exposure sum ?
80
Minimum pKa ?
10
% buried
96
Peptide accession
Q13315
Residue number A
2930
Residue number B
2931
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 2930 of Serine-protein kinase ATM
Cysteine 2931 of Serine-protein kinase ATM
7sic B 977 B 987
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 977 and 987. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
90
Peptide accession
Q13315
Residue number A
977
Residue number B
987
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 977 of Serine-protein kinase ATM
Cysteine 987 of Serine-protein kinase ATM
6k9l B 2753 B 2770
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 2753 and 2770. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
6k9l
Structure name
4
Structure deposition date
2019-06-16
Thiol separation (Å)
8
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
50
Peptide accession
Q13315
Residue number A
2753
Residue number B
2770
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 2753 of Serine-protein kinase ATM
Cysteine 2770 of Serine-protein kinase ATM
7sic A 1494 A 1495
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1494 and 1495. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
77
Minimum pKa ?
12
% buried
90
Peptide accession
Q13315
Residue number A
1494
Residue number B
1495
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1494 of Serine-protein kinase ATM
Cysteine 1495 of Serine-protein kinase ATM
7ni4 B 2801 B 2824
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 2801 and 2824. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7ni4
Structure name
human atm kinase domain with bound m4076 inhibitor
Structure deposition date
2021-02-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
11
% buried
71
Peptide accession
Q13315
Residue number A
2801
Residue number B
2824
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 2801 of Serine-protein kinase ATM
Cysteine 2824 of Serine-protein kinase ATM
7ni5 A 1736 A 1831
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1736 and 1831. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
72
Minimum pKa ?
12
% buried
88
Peptide accession
Q13315
Residue number A
1736
Residue number B
1831
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1736 of Serine-protein kinase ATM
Cysteine 1831 of Serine-protein kinase ATM
7sic A 1164 A 1168
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1164 and 1168. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
82
Peptide accession
Q13315
Residue number A
1164
Residue number B
1168
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1164 of Serine-protein kinase ATM
Cysteine 1168 of Serine-protein kinase ATM
7ni5 A 1482 A 1495
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 1482 and 1495. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
59
Minimum pKa ?
11
% buried
47
Peptide accession
Q13315
Residue number A
1482
Residue number B
1495
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 1482 of Serine-protein kinase ATM
Cysteine 1495 of Serine-protein kinase ATM
7sic A 540 A 541
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 540 and 541. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
11
% buried
69
Peptide accession
Q13315
Residue number A
540
Residue number B
541
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 540 of Serine-protein kinase ATM
Cysteine 541 of Serine-protein kinase ATM
7ni5 B 532 B 541
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 532 and 541. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
61
Minimum pKa ?
11
% buried
75
Peptide accession
Q13315
Residue number A
532
Residue number B
541
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 532 of Serine-protein kinase ATM
Cysteine 541 of Serine-protein kinase ATM
7ni5 A 783 A 907
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 783 and 907. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
86
Minimum pKa ?
13
% buried
100
Peptide accession
Q13315
Residue number A
783
Residue number B
907
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 783 of Serine-protein kinase ATM
Cysteine 907 of Serine-protein kinase ATM
7ni4 A 2337 A 2341
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 2337 and 2341. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
7ni4
Structure name
human atm kinase domain with bound m4076 inhibitor
Structure deposition date
2021-02-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
92
Minimum pKa ?
11
% buried
84
Peptide accession
Q13315
Residue number A
2337
Residue number B
2341
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 2337 of Serine-protein kinase ATM
Cysteine 2341 of Serine-protein kinase ATM
7ni5 B 819 B 905
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 819 and 905. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
13
% buried
100
Peptide accession
Q13315
Residue number A
819
Residue number B
905
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 819 of Serine-protein kinase ATM
Cysteine 905 of Serine-protein kinase ATM
7ni5 A 728 A 730
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 728 and 730. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
30
PDB code
7ni5
Structure name
human atm kinase with bound inhibitor ku-55933
Structure deposition date
2021-02-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
76
Peptide accession
Q13315
Residue number A
728
Residue number B
730
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 728 of Serine-protein kinase ATM
Cysteine 730 of Serine-protein kinase ATM
7sic B 786 B 907
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 786 and 907. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
84
Minimum pKa ?
12
% buried
100
Peptide accession
Q13315
Residue number A
786
Residue number B
907
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 786 of Serine-protein kinase ATM
Cysteine 907 of Serine-protein kinase ATM
7sic B 977 B 1045
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 977 and 1045. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
71
Minimum pKa ?
12
% buried
95
Peptide accession
Q13315
Residue number A
977
Residue number B
1045
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 977 of Serine-protein kinase ATM
Cysteine 1045 of Serine-protein kinase ATM
7sid A 157 A 987
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 157 and 987. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
28
PDB code
7sid
Structure name
human atm dimer bound to nbs1
Structure deposition date
2021-10-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
87
Peptide accession
Q13315
Residue number A
157
Residue number B
987
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 157 of Serine-protein kinase ATM
Cysteine 987 of Serine-protein kinase ATM
7sic A 905 A 907
A redox-regulated disulphide may form within Serine-protein kinase ATM between cysteines 905 and 907. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
25
PDB code
7sic
Structure name
human atm dimer
Structure deposition date
2021-10-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
84
Minimum pKa ?
13
% buried
100
Peptide accession
Q13315
Residue number A
905
Residue number B
907
Peptide name
Serine-protein kinase ATM
Ligandability
Cysteine 905 of Serine-protein kinase ATM
Cysteine 907 of Serine-protein kinase ATM
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