Interleukin-18 receptor 1
Intramolecular
Cysteine 43 and cysteine 81
Cysteine 119 and cysteine 158
Cysteine 22 and cysteine 41
Cysteine 140 and cysteine 185
Cysteine 237 and cysteine 298
Cysteine 22 and cysteine 81
Cysteine 22 and cysteine 43
Cysteine 41 and cysteine 43
Cysteine 41 and cysteine 81
3wo4 B 43 B 81
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 43 and 81.
Details
Redox score ?
87
PDB code
3wo4
Structure name
crystal structure of the il-18 signaling ternary complex
Structure deposition date
2013-12-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
43
Residue number B
81
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 43 of Interleukin-18 receptor 1
Cysteine 81 of Interleukin-18 receptor 1
3wo3 J 119 J 158
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 119 and 158.
Details
Redox score ?
86
PDB code
3wo3
Structure name
crystal structure of il-18 in complex with il-18 receptor alpha
Structure deposition date
2013-12-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
119
Residue number B
158
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 119 of Interleukin-18 receptor 1
Cysteine 158 of Interleukin-18 receptor 1
3wo3 D 22 D 41
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 22 and 41.
Details
Redox score ?
82
PDB code
3wo3
Structure name
crystal structure of il-18 in complex with il-18 receptor alpha
Structure deposition date
2013-12-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
22
Residue number B
41
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 22 of Interleukin-18 receptor 1
Cysteine 41 of Interleukin-18 receptor 1
3wo4 B 140 B 185
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 140 and 185.
Details
Redox score ?
82
PDB code
3wo4
Structure name
crystal structure of the il-18 signaling ternary complex
Structure deposition date
2013-12-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
140
Residue number B
185
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 140 of Interleukin-18 receptor 1
Cysteine 185 of Interleukin-18 receptor 1
3wo3 F 237 F 298
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 237 and 298.
Details
Redox score ?
79
PDB code
3wo3
Structure name
crystal structure of il-18 in complex with il-18 receptor alpha
Structure deposition date
2013-12-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
237
Residue number B
298
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 237 of Interleukin-18 receptor 1
Cysteine 298 of Interleukin-18 receptor 1
3wo3 L 22 L 81
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 22 and 81. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
3wo3
Structure name
crystal structure of il-18 in complex with il-18 receptor alpha
Structure deposition date
2013-12-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
22
Residue number B
81
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 22 of Interleukin-18 receptor 1
Cysteine 81 of Interleukin-18 receptor 1
3wo3 H 22 H 43
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 22 and 43. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
3wo3
Structure name
crystal structure of il-18 in complex with il-18 receptor alpha
Structure deposition date
2013-12-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
22
Residue number B
43
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 22 of Interleukin-18 receptor 1
Cysteine 43 of Interleukin-18 receptor 1
3wo4 B 41 B 43
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 41 and 43. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
3wo4
Structure name
crystal structure of the il-18 signaling ternary complex
Structure deposition date
2013-12-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
41
Residue number B
43
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 41 of Interleukin-18 receptor 1
Cysteine 43 of Interleukin-18 receptor 1
3wo3 L 41 L 81
A redox-regulated disulphide may form within Interleukin-18 receptor 1 between cysteines 41 and 81. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3wo3
Structure name
crystal structure of il-18 in complex with il-18 receptor alpha
Structure deposition date
2013-12-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
43
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13478
Residue number A
41
Residue number B
81
Peptide name
Interleukin-18 receptor 1
Ligandability
Cysteine 41 of Interleukin-18 receptor 1
Cysteine 81 of Interleukin-18 receptor 1
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