ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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CD166 antigen

Intramolecular
Cysteine 43 and cysteine 113
Cysteine 157 and cysteine 220
A redox-regulated disulphide may form within CD166 antigen between cysteines 43 and 113.

Details

Redox score ?
83
PDB code
5a2f
Structure name
two membrane distal igsf domains of cd166
Structure deposition date
2015-05-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13740
Residue number A
43
Residue number B
113
Peptide name
CD166 antigen

Ligandability

Cysteine 43 of CD166 antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 113 of CD166 antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within CD166 antigen between cysteines 157 and 220.

Details

Redox score ?
80
PDB code
5a2f
Structure name
two membrane distal igsf domains of cd166
Structure deposition date
2015-05-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13740
Residue number A
157
Residue number B
220
Peptide name
CD166 antigen

Ligandability

Cysteine 157 of CD166 antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 220 of CD166 antigen

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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