ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Phorbol-12-myristate-13-acetate-induced protein 1

Intermolecular
Cysteine 55 of Bcl-2-related protein A1 and cysteine 25
A redox-regulated disulphide may form between cysteine 55 of Bcl-2-related protein A1 and cysteine 25 of Phorbol-12-myristate-13-acetate-induced protein 1.

Details

Redox score ?
72
PDB code
3mqp
Structure name
crystal structure of human bfl-1 in complex with noxa bh3 peptide, northeast structural genomics consortium target hr2930
Structure deposition date
2010-04-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
42
Peptide A name
Bcl-2-related protein A1
Peptide B name
Phorbol-12-myristate-13-acetate-induced protein 1
Peptide A accession
Q16548
Peptide B accession
Q13794
Peptide A residue number
55
Peptide B residue number
25

Ligandability

Cysteine 55 of Bcl-2-related protein A1

Cysteine 25 of Phorbol-12-myristate-13-acetate-induced protein 1

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