Bone morphogenetic protein receptor type-2
Intramolecular
Cysteine 60 and cysteine 84
Cysteine 94 and cysteine 117
Cysteine 34 and cysteine 66
Cysteine 99 and cysteine 116
Cysteine 118 and cysteine 123
Cysteine 34 and cysteine 60
Cysteine 99 and cysteine 118
Cysteine 66 and cysteine 123
Cysteine 60 and cysteine 66
Cysteine 99 and cysteine 123
More...Cysteine 34 and cysteine 84
Cysteine 66 and cysteine 118
Cysteine 34 and cysteine 123
Cysteine 116 and cysteine 118
Cysteine 94 and cysteine 118
Cysteine 94 and cysteine 99
Cysteine 34 and cysteine 118
Cysteine 94 and cysteine 123
Cysteine 99 and cysteine 117
Cysteine 66 and cysteine 84
Cysteine 66 and cysteine 99
Cysteine 117 and cysteine 118
Cysteine 116 and cysteine 123
Cysteine 94 and cysteine 116
Cysteine 116 and cysteine 117
Cysteine 66 and cysteine 94
Cysteine 302 and cysteine 420
Cysteine 60 and cysteine 123
Cysteine 34 and cysteine 99
Cysteine 117 and cysteine 123
Cysteine 66 and cysteine 116
Cysteine 34 and cysteine 116
Cysteine 60 and cysteine 118
Cysteine 66 and cysteine 117
2hlq A 60 A 84
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 60 and 84.
Details
Redox score ?
83
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
60
Residue number B
84
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 60 of Bone morphogenetic protein receptor type-2
Cysteine 84 of Bone morphogenetic protein receptor type-2
7u5o G 94 G 117
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 94 and 117.
Details
Redox score ?
82
PDB code
7u5o
Structure name
crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in complex with activin-b
Structure deposition date
2022-03-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
94
Residue number B
117
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 94 of Bone morphogenetic protein receptor type-2
Cysteine 117 of Bone morphogenetic protein receptor type-2
7ppa C 34 C 66
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 66.
Details
Redox score ?
81
PDB code
7ppa
Structure name
high resolution structure of bone morphogenetic protein receptor type ii (bmprii) extracellular domain in complex with bmp10
Structure deposition date
2021-09-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
66
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 66 of Bone morphogenetic protein receptor type-2
7ppb B 99 B 116
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 99 and 116.
Details
Redox score ?
81
PDB code
7ppb
Structure name
2
Structure deposition date
2021-09-13
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
99
Residue number B
116
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 99 of Bone morphogenetic protein receptor type-2
Cysteine 116 of Bone morphogenetic protein receptor type-2
2hlq A 118 A 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 118 and 123.
Details
Redox score ?
79
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
118
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 118 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
7ppa C 34 C 60
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 60.
Details
Redox score ?
77
PDB code
7ppa
Structure name
high resolution structure of bone morphogenetic protein receptor type ii (bmprii) extracellular domain in complex with bmp10
Structure deposition date
2021-09-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
60
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 60 of Bone morphogenetic protein receptor type-2
2hlq A 99 A 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 99 and 118.
Details
Redox score ?
73
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
99
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 99 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
2hlq A 66 A 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 123.
Details
Redox score ?
68
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
66
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
2hlq A 60 A 66
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 60 and 66.
Details
Redox score ?
63
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
60
Residue number B
66
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 60 of Bone morphogenetic protein receptor type-2
Cysteine 66 of Bone morphogenetic protein receptor type-2
2hlq A 99 A 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 99 and 123.
Details
Redox score ?
63
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
6
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
99
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 99 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
7ppb B 34 B 84
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 84.
Details
Redox score ?
62
PDB code
7ppb
Structure name
2
Structure deposition date
2021-09-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
84
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 84 of Bone morphogenetic protein receptor type-2
2hlq A 66 A 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 118.
Details
Redox score ?
61
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
66
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
7ppb B 34 B 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 123.
Details
Redox score ?
60
PDB code
7ppb
Structure name
2
Structure deposition date
2021-09-13
Thiol separation (Å)
6
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
2hlq A 116 A 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 116 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
6
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
116
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 116 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
2hlq A 94 A 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 94 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
6
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
94
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 94 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
2hlq A 94 A 99
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 94 and 99. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
94
Residue number B
99
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 94 of Bone morphogenetic protein receptor type-2
Cysteine 99 of Bone morphogenetic protein receptor type-2
7u5o E 34 E 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7u5o
Structure name
crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in complex with activin-b
Structure deposition date
2022-03-02
Thiol separation (Å)
7
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
2hlq A 94 A 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 94 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
94
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 94 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
2hlq A 99 A 117
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 99 and 117. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
99
Residue number B
117
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 99 of Bone morphogenetic protein receptor type-2
Cysteine 117 of Bone morphogenetic protein receptor type-2
2hlq A 66 A 84
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 84. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
66
Residue number B
84
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 84 of Bone morphogenetic protein receptor type-2
2hlq A 66 A 99
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 99. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
66
Residue number B
99
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 99 of Bone morphogenetic protein receptor type-2
2hlq A 117 A 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 117 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
117
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 117 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
2hlq A 116 A 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 116 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
116
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 116 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
2hlq A 94 A 116
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 94 and 116. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
94
Residue number B
116
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 94 of Bone morphogenetic protein receptor type-2
Cysteine 116 of Bone morphogenetic protein receptor type-2
2hlq A 116 A 117
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 116 and 117. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
116
Residue number B
117
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 116 of Bone morphogenetic protein receptor type-2
Cysteine 117 of Bone morphogenetic protein receptor type-2
2hlq A 66 A 94
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 94. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
66
Residue number B
94
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 94 of Bone morphogenetic protein receptor type-2
3g2f B 302 B 420
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 302 and 420. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
3g2f
Structure name
crystal structure of the kinase domain of bone morphogenetic protein receptor type ii (bmpr2) at 2
Structure deposition date
2009-01-31
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
12
% buried
94
Peptide accession
Q13873
Residue number A
302
Residue number B
420
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 302 of Bone morphogenetic protein receptor type-2
Cysteine 420 of Bone morphogenetic protein receptor type-2
7ppa C 60 C 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 60 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
7ppa
Structure name
high resolution structure of bone morphogenetic protein receptor type ii (bmprii) extracellular domain in complex with bmp10
Structure deposition date
2021-09-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
60
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 60 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
7ppc L 34 L 99
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 99. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
7ppc
Structure name
ternary signalling complex of bmp10 bound to alk1 and bmprii
Structure deposition date
2021-09-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
99
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 99 of Bone morphogenetic protein receptor type-2
2hlq A 117 A 123
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 117 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
117
Residue number B
123
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 117 of Bone morphogenetic protein receptor type-2
Cysteine 123 of Bone morphogenetic protein receptor type-2
7u5o E 66 E 116
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 116. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
7u5o
Structure name
crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in complex with activin-b
Structure deposition date
2022-03-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
66
Residue number B
116
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 116 of Bone morphogenetic protein receptor type-2
7u5o E 34 E 116
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 34 and 116. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
7u5o
Structure name
crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in complex with activin-b
Structure deposition date
2022-03-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
34
Residue number B
116
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 34 of Bone morphogenetic protein receptor type-2
Cysteine 116 of Bone morphogenetic protein receptor type-2
7u5o G 60 G 118
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 60 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
7u5o
Structure name
crystal structure of the bone morphogenetic protein receptor type 2 ligand binding domain in complex with activin-b
Structure deposition date
2022-03-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q13873
Residue number A
60
Residue number B
118
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 60 of Bone morphogenetic protein receptor type-2
Cysteine 118 of Bone morphogenetic protein receptor type-2
2hlq A 66 A 117
A redox-regulated disulphide may form within Bone morphogenetic protein receptor type-2 between cysteines 66 and 117. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
2hlq
Structure name
crystal structure of the extracellular domain of the type ii bmp receptor
Structure deposition date
2006-07-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q4ZG08
Residue number A
66
Residue number B
117
Peptide name
Bone morphogenetic protein receptor type-2
Ligandability
Cysteine 66 of Bone morphogenetic protein receptor type-2
Cysteine 117 of Bone morphogenetic protein receptor type-2
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