ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Cytoskeleton-associated protein 5

Intramolecular
Cysteine 1019 and cysteine 1026
A redox-regulated disulphide may form within Cytoskeleton-associated protein 5 between cysteines 1019 and 1026. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
4qmj
Structure name
the xmap215 family drives microtubule polymerization using a structurally diverse tog array
Structure deposition date
2014-06-16
Thiol separation (Å)
10
Half-sphere exposure sum ?
74
Minimum pKa ?
12
% buried
87
Peptide accession
Q14008
Residue number A
1019
Residue number B
1026
Peptide name
Cytoskeleton-associated protein 5

Ligandability

Cysteine 1019 of Cytoskeleton-associated protein 5

Cysteine 1026 of Cytoskeleton-associated protein 5

If this tool was useful for finding a disulphide, please cite: