ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Four and a half LIM domains protein 2

Intramolecular
Cysteine 129 and cysteine 150
Cysteine 129 and cysteine 132
Cysteine 251 and cysteine 254 L
Cysteine 251 and cysteine 275
Cysteine 251 and cysteine 272
Cysteine 68 and cysteine 89
Cysteine 68 and cysteine 71
Cysteine 40 and cysteine 43
Cysteine 7 and cysteine 10 L
Cysteine 101 and cysteine 104
More...
Cysteine 129 and cysteine 153
Cysteine 7 and cysteine 28 L
Cysteine 7 and cysteine 31 L
Cysteine 40 and cysteine 65
Cysteine 101 and cysteine 126
Cysteine 68 and cysteine 92
Cysteine 221 and cysteine 224
Cysteine 71 and cysteine 92
Cysteine 254 and cysteine 272 L
Cysteine 272 and cysteine 275
Cysteine 221 and cysteine 248 L
Cysteine 28 and cysteine 31
Cysteine 89 and cysteine 92
Cysteine 132 and cysteine 150
Cysteine 132 and cysteine 153
Cysteine 224 and cysteine 248 L
Cysteine 43 and cysteine 65
Cysteine 10 and cysteine 28 L
Cysteine 254 and cysteine 275 L
Cysteine 10 and cysteine 31 L
Cysteine 104 and cysteine 126
Cysteine 150 and cysteine 153
Cysteine 71 and cysteine 89
Cysteine 40 and cysteine 51
Cysteine 43 and cysteine 51
Cysteine 49 and cysteine 51
Cysteine 51 and cysteine 65
A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 129 and 150 (36 and 57 respectively in this structure).

Details

Redox score ?
90
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
3
Half-sphere exposure sum ?
57
Minimum pKa ?
5
% buried
8
Peptide accession
Q14192
Residue number A
129
Residue number B
150
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 129 of Four and a half LIM domains protein 2

Cysteine 150 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 129 and 132 (36 and 39 respectively in this structure).

Details

Redox score ?
90
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
6
Peptide accession
Q14192
Residue number A
129
Residue number B
132
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 129 of Four and a half LIM domains protein 2

Cysteine 132 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 251 and 254 (38 and 41 respectively in this structure).

Details

Redox score ?
88
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
2
Peptide accession
Q14192
Residue number A
251
Residue number B
254
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 251 of Four and a half LIM domains protein 2

Cysteine 254 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 251 and 275 (38 and 62 respectively in this structure).

Details

Redox score ?
88
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
5
% buried
2
Peptide accession
Q14192
Residue number A
251
Residue number B
275
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 251 of Four and a half LIM domains protein 2

Cysteine 275 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 251 and 272 (38 and 59 respectively in this structure).

Details

Redox score ?
88
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
2
Peptide accession
Q14192
Residue number A
251
Residue number B
272
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 251 of Four and a half LIM domains protein 2

Cysteine 272 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 68 and 89.

Details

Redox score ?
88
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
5
% buried
0
Peptide accession
Q14192
Residue number A
68
Residue number B
89
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 68 of Four and a half LIM domains protein 2

Cysteine 89 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 68 and 71.

Details

Redox score ?
88
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
5
% buried
0
Peptide accession
Q14192
Residue number A
68
Residue number B
71
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 68 of Four and a half LIM domains protein 2

Cysteine 71 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 40 and 43.

Details

Redox score ?
88
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
8
Peptide accession
Q14192
Residue number A
40
Residue number B
43
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 40 of Four and a half LIM domains protein 2

Cysteine 43 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 7 and 10.

Details

Redox score ?
88
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
0
Peptide accession
Q14192
Residue number A
7
Residue number B
10
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 7 of Four and a half LIM domains protein 2

Cysteine 10 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 101 and 104 (8 and 11 respectively in this structure).

Details

Redox score ?
87
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
5
% buried
4
Peptide accession
Q14192
Residue number A
101
Residue number B
104
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 101 of Four and a half LIM domains protein 2

Cysteine 104 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 129 and 153 (36 and 60 respectively in this structure).

Details

Redox score ?
87
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
5
% buried
6
Peptide accession
Q14192
Residue number A
129
Residue number B
153
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 129 of Four and a half LIM domains protein 2

Cysteine 153 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 7 and 28.

Details

Redox score ?
87
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
5
% buried
2
Peptide accession
Q14192
Residue number A
7
Residue number B
28
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 7 of Four and a half LIM domains protein 2

Cysteine 28 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 7 and 31.

Details

Redox score ?
87
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
5
% buried
2
Peptide accession
Q14192
Residue number A
7
Residue number B
31
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 7 of Four and a half LIM domains protein 2

Cysteine 31 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 40 and 65.

Details

Redox score ?
85
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
6
% buried
12
Peptide accession
Q14192
Residue number A
40
Residue number B
65
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 40 of Four and a half LIM domains protein 2

Cysteine 65 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 101 and 126 (8 and 33 respectively in this structure).

Details

Redox score ?
85
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
5
Peptide accession
Q14192
Residue number A
101
Residue number B
126
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 101 of Four and a half LIM domains protein 2

Cysteine 126 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 68 and 92.

Details

Redox score ?
85
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
5
% buried
0
Peptide accession
Q14192
Residue number A
68
Residue number B
92
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 68 of Four and a half LIM domains protein 2

Cysteine 92 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 221 and 224 (8 and 11 respectively in this structure).

Details

Redox score ?
84
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
7
% buried
4
Peptide accession
Q14192
Residue number A
221
Residue number B
224
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 221 of Four and a half LIM domains protein 2

Cysteine 224 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 71 and 92.

Details

Redox score ?
83
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
3
Half-sphere exposure sum ?
40
Minimum pKa ?
8
% buried
0
Peptide accession
Q14192
Residue number A
71
Residue number B
92
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 71 of Four and a half LIM domains protein 2

Cysteine 92 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 254 and 272 (41 and 59 respectively in this structure).

Details

Redox score ?
82
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
0
Peptide accession
Q14192
Residue number A
254
Residue number B
272
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 254 of Four and a half LIM domains protein 2

Cysteine 272 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 272 and 275 (59 and 62 respectively in this structure).

Details

Redox score ?
82
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
8
% buried
0
Peptide accession
Q14192
Residue number A
272
Residue number B
275
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 272 of Four and a half LIM domains protein 2

Cysteine 275 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 221 and 248 (8 and 35 respectively in this structure).

Details

Redox score ?
81
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
7
% buried
4
Peptide accession
Q14192
Residue number A
221
Residue number B
248
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 221 of Four and a half LIM domains protein 2

Cysteine 248 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 28 and 31.

Details

Redox score ?
80
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
3
Half-sphere exposure sum ?
54
Minimum pKa ?
9
% buried
4
Peptide accession
Q14192
Residue number A
28
Residue number B
31
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 28 of Four and a half LIM domains protein 2

Cysteine 31 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 89 and 92.

Details

Redox score ?
80
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
8
% buried
0
Peptide accession
Q14192
Residue number A
89
Residue number B
92
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 89 of Four and a half LIM domains protein 2

Cysteine 92 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 132 and 150 (39 and 57 respectively in this structure).

Details

Redox score ?
80
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
2
Peptide accession
Q14192
Residue number A
132
Residue number B
150
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 132 of Four and a half LIM domains protein 2

Cysteine 150 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 132 and 153 (39 and 60 respectively in this structure).

Details

Redox score ?
79
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
8
% buried
0
Peptide accession
Q14192
Residue number A
132
Residue number B
153
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 132 of Four and a half LIM domains protein 2

Cysteine 153 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 224 and 248 (11 and 35 respectively in this structure).

Details

Redox score ?
78
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
0
Peptide accession
Q14192
Residue number A
224
Residue number B
248
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 224 of Four and a half LIM domains protein 2

Cysteine 248 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 43 and 65.

Details

Redox score ?
78
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
3
Half-sphere exposure sum ?
44
Minimum pKa ?
10
% buried
4
Peptide accession
Q14192
Residue number A
43
Residue number B
65
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 43 of Four and a half LIM domains protein 2

Cysteine 65 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 10 and 28.

Details

Redox score ?
78
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
9
% buried
2
Peptide accession
Q14192
Residue number A
10
Residue number B
28
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 10 of Four and a half LIM domains protein 2

Cysteine 28 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 254 and 275 (41 and 62 respectively in this structure).

Details

Redox score ?
77
PDB code
1x4l
Structure name
solution structure of lim domain in four and a half lim domains protein 2
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
10
% buried
0
Peptide accession
Q14192
Residue number A
254
Residue number B
275
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 254 of Four and a half LIM domains protein 2

Cysteine 275 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 10 and 31.

Details

Redox score ?
77
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
3
Half-sphere exposure sum ?
44
Minimum pKa ?
11
% buried
2
Peptide accession
Q14192
Residue number A
10
Residue number B
31
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 10 of Four and a half LIM domains protein 2

Cysteine 31 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 104 and 126 (11 and 33 respectively in this structure).

Details

Redox score ?
76
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
9
% buried
2
Peptide accession
Q14192
Residue number A
104
Residue number B
126
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 104 of Four and a half LIM domains protein 2

Cysteine 126 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 150 and 153 (57 and 60 respectively in this structure).

Details

Redox score ?
76
PDB code
1x4k
Structure name
solution structure of lim domain in lim-protein 3
Structure deposition date
2005-05-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
9
% buried
2
Peptide accession
Q14192
Residue number A
150
Residue number B
153
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 150 of Four and a half LIM domains protein 2

Cysteine 153 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 71 and 89.

Details

Redox score ?
76
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
10
% buried
0
Peptide accession
Q14192
Residue number A
71
Residue number B
89
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 71 of Four and a half LIM domains protein 2

Cysteine 89 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 40 and 51. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
60
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
9
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
8
Peptide accession
Q14192
Residue number A
40
Residue number B
51
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 40 of Four and a half LIM domains protein 2

Cysteine 51 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 43 and 51. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
32
Minimum pKa ?
10
% buried
0
Peptide accession
Q14192
Residue number A
43
Residue number B
51
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 43 of Four and a half LIM domains protein 2

Cysteine 51 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 49 and 51. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
38
Minimum pKa ?
10
% buried
0
Peptide accession
Q14192
Residue number A
49
Residue number B
51
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 49 of Four and a half LIM domains protein 2

Cysteine 51 of Four and a half LIM domains protein 2

A redox-regulated disulphide may form within Four and a half LIM domains protein 2 between cysteines 51 and 65. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
51
PDB code
2miu
Structure name
structure of fhl2 lim adaptor and its interaction with ski
Structure deposition date
2013-12-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
44
Minimum pKa ?
10
% buried
4
Peptide accession
Q14192
Residue number A
51
Residue number B
65
Peptide name
Four and a half LIM domains protein 2

Ligandability

Cysteine 51 of Four and a half LIM domains protein 2

Cysteine 65 of Four and a half LIM domains protein 2

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