Dihydropyrimidinase-related protein 1

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of Dihydropyrimidinase-related protein 1 at cysteines 323 and 323. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4b3z

Structure name

structure of the human collapsin response mediator protein-1, a lung cancer suppressor

Structure deposition date

2012-07-27

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Dihydropyrimidinase-related protein 1

Peptide B name

Dihydropyrimidinase-related protein 1

Peptide A accession

Q14194

Peptide B accession

Q14194

Peptide A residue number

323

Peptide B residue number

323

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Dihydropyrimidinase-related protein 1 between cysteines 132 and 133. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?