Glucokinase regulatory protein

Intramolecular

A redox-regulated disulphide may form within Glucokinase regulatory protein between cysteines 193 and 194. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4olh

Structure name

human gkrp bound to amg5106 and sorbitol-6-phosphate

Structure deposition date

2014-01-23

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q14397

Residue number A

193

Residue number B

194

Peptide name

Glucokinase regulatory protein

Ligandability

Cysteine 193 of Glucokinase regulatory protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.