ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Indian hedgehog protein

Intramolecular
Cysteine 107 and cysteine 188
A redox-regulated disulphide may form within Indian hedgehog protein between cysteines 107 and 188. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
3k7g
Structure name
crystal structure of the indian hedgehog n-terminal signalling domain
Structure deposition date
2009-10-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
92
Minimum pKa ?
12
% buried
100
Peptide accession
Q14623
Residue number A
107
Residue number B
188
Peptide name
Indian hedgehog protein

Ligandability

Cysteine 107 of Indian hedgehog protein

Cysteine 188 of Indian hedgehog protein

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