Nuclear receptor subfamily 1 group I member 3

A redox-regulated disulphide may form between two units of Nuclear receptor subfamily 1 group I member 3 at cysteines 233 and 233. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1xnx

Structure name

crystal structure of constitutive androstane receptor

Structure deposition date

2004-10-05

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Nuclear receptor subfamily 1 group I member 3

Peptide B name

Nuclear receptor subfamily 1 group I member 3

Peptide A accession

O35627

Peptide B accession

O35627

Peptide A residue number

233

Peptide B residue number

233

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group I member 3 between cysteines 221 and 233. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1xls

Structure name

crystal structure of the mouse car/rxr lbd heterodimer bound to tcpobop and 9cra and a tif2 peptide containg the third lxxll motifs

Structure deposition date

2004-09-30

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O35627

Residue number A

221

Residue number B

233

Peptide name

Nuclear receptor subfamily 1 group I member 3

Ligandability

Cysteine 221 of Nuclear receptor subfamily 1 group I member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 233 of Nuclear receptor subfamily 1 group I member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group I member 3 between cysteines 229 and 233. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?