Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Intramolecular
Cysteine 420 and cysteine 423
Cysteine 423 and cysteine 440
Cysteine 423 and cysteine 443
Cysteine 320 and cysteine 328
Cysteine 440 and cysteine 443
Cysteine 420 and cysteine 440
Cysteine 423 and cysteine 501
Cysteine 315 and cysteine 338 L
Cysteine 420 and cysteine 421
Cysteine 443 and cysteine 501
More...Cysteine 420 and cysteine 443
Cysteine 421 and cysteine 423
Cysteine 320 and cysteine 338 L
Cysteine 64 and cysteine 79 L
Cysteine 328 and cysteine 338 L
Cysteine 421 and cysteine 443
3jue A 420 A 423
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 420 and 423.
Details
Redox score ?
81
PDB code
3jue
Structure name
crystal structure of arfgap and ank repeat domain of acap1
Structure deposition date
2009-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
4
% buried
nan
Peptide accession
Q15027
Residue number A
420
Residue number B
423
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 420 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 423 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p A 423 A 440
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 423 and 440.
Details
Redox score ?
78
PDB code
4f1p
Structure name
crystal structure of mutant s554d for arfgap and ank repeat domain of acap1
Structure deposition date
2012-05-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
6
% buried
55
Peptide accession
Q15027
Residue number A
423
Residue number B
440
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 423 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 440 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p B 423 B 443
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 423 and 443.
Details
Redox score ?
77
PDB code
4f1p
Structure name
crystal structure of mutant s554d for arfgap and ank repeat domain of acap1
Structure deposition date
2012-05-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
80
Minimum pKa ?
6
% buried
70
Peptide accession
Q15027
Residue number A
423
Residue number B
443
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 423 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 443 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4nsw B 320 B 328
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 320 and 328.
Details
Redox score ?
64
PDB code
4nsw
Structure name
crystal structure of the bar-ph domain of acap1
Structure deposition date
2013-11-29
Thiol separation (Å)
6
Half-sphere exposure sum ?
57
Minimum pKa ?
10
% buried
48
Peptide accession
Q15027
Residue number A
320
Residue number B
328
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 320 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 328 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3jue A 440 A 443
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 440 and 443.
Details
Redox score ?
60
PDB code
3jue
Structure name
crystal structure of arfgap and ank repeat domain of acap1
Structure deposition date
2009-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
14
% buried
70
Peptide accession
Q15027
Residue number A
440
Residue number B
443
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 440 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 443 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p B 420 B 440
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 420 and 440.
Details
Redox score ?
60
PDB code
4f1p
Structure name
crystal structure of mutant s554d for arfgap and ank repeat domain of acap1
Structure deposition date
2012-05-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
14
% buried
nan
Peptide accession
Q15027
Residue number A
420
Residue number B
440
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 420 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 440 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p B 423 B 501
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 423 and 501. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
4f1p
Structure name
crystal structure of mutant s554d for arfgap and ank repeat domain of acap1
Structure deposition date
2012-05-07
Thiol separation (Å)
8
Half-sphere exposure sum ?
58
Minimum pKa ?
6
% buried
30
Peptide accession
Q15027
Residue number A
423
Residue number B
501
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 423 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 501 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4nsw B 315 B 338
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 315 and 338. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
4nsw
Structure name
crystal structure of the bar-ph domain of acap1
Structure deposition date
2013-11-29
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
52
Peptide accession
Q15027
Residue number A
315
Residue number B
338
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 315 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 338 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3jue B 420 B 421
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 420 and 421. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
3jue
Structure name
crystal structure of arfgap and ank repeat domain of acap1
Structure deposition date
2009-09-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
87
Minimum pKa ?
11
% buried
nan
Peptide accession
Q15027
Residue number A
420
Residue number B
421
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 420 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 421 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p B 443 B 501
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 443 and 501. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
4f1p
Structure name
crystal structure of mutant s554d for arfgap and ank repeat domain of acap1
Structure deposition date
2012-05-07
Thiol separation (Å)
10
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
39
Peptide accession
Q15027
Residue number A
443
Residue number B
501
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 443 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 501 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4f1p A 420 A 443
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 420 and 443. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
4f1p
Structure name
crystal structure of mutant s554d for arfgap and ank repeat domain of acap1
Structure deposition date
2012-05-07
Thiol separation (Å)
4
Half-sphere exposure sum ?
81
Minimum pKa ?
24
% buried
nan
Peptide accession
Q15027
Residue number A
420
Residue number B
443
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 420 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 443 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3jue B 421 B 423
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 421 and 423. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
3jue
Structure name
crystal structure of arfgap and ank repeat domain of acap1
Structure deposition date
2009-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
87
Minimum pKa ?
6
% buried
80
Peptide accession
Q15027
Residue number A
421
Residue number B
423
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 421 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 423 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4nsw B 320 B 338
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 320 and 338. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
4nsw
Structure name
crystal structure of the bar-ph domain of acap1
Structure deposition date
2013-11-29
Thiol separation (Å)
10
Half-sphere exposure sum ?
53
Minimum pKa ?
11
% buried
60
Peptide accession
Q15027
Residue number A
320
Residue number B
338
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 320 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 338 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
4nsw B 64 B 79
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 64 and 79. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
4nsw
Structure name
crystal structure of the bar-ph domain of acap1
Structure deposition date
2013-11-29
Thiol separation (Å)
10
Half-sphere exposure sum ?
65
Minimum pKa ?
10
% buried
62
Peptide accession
Q15027
Residue number A
64
Residue number B
79
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 64 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 79 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
5h3d D 328 D 338
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 328 and 338. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
5h3d
Structure name
helical structure of membrane tubules decorated by acap1 (barph doamin) protein by cryo-electron microscopy and md simulation
Structure deposition date
2016-10-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
11
% buried
71
Peptide accession
Q15027
Residue number A
328
Residue number B
338
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 328 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 338 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
3jue A 421 A 443
A redox-regulated disulphide may form within Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 between cysteines 421 and 443. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
33
PDB code
3jue
Structure name
crystal structure of arfgap and ank repeat domain of acap1
Structure deposition date
2009-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
93
Minimum pKa ?
12
% buried
90
Peptide accession
Q15027
Residue number A
421
Residue number B
443
Peptide name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Ligandability
Cysteine 421 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Cysteine 443 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
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