ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Transcription factor E2F5

Intramolecular
Cysteine 179 and cysteine 181
A redox-regulated disulphide may form within Transcription factor E2F5 between cysteines 179 and 181. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
5tuv
Structure name
crystal structure of the e2f5-dp1-p107 ternary complex
Structure deposition date
2016-11-07
Thiol separation (Å)
8
Half-sphere exposure sum ?
53
Minimum pKa ?
10
% buried
42
Peptide accession
Q15329
Residue number A
179
Residue number B
181
Peptide name
Transcription factor E2F5

Ligandability

Cysteine 179 of Transcription factor E2F5

Cysteine 181 of Transcription factor E2F5

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