a tool for identifying drug-targetable redox-active disulphides

Transmembrane emp24 domain-containing protein 2

Intramolecular

Cysteine 32 and cysteine 93

A redox-regulated disulphide may form within Transmembrane emp24 domain-containing protein 2 between cysteines 32 and 93.

Details

Redox score ?

82

PDB code

Structure name

crystal structure of p24beta1 gold domain

Structure deposition date

2015-10-23

Thiol separation (Å)

2

Half-sphere exposure sum ?

63

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

32

Residue number B

93

Peptide name

Transmembrane emp24 domain-containing protein 2

Ligandability

Cysteine 32 of Transmembrane emp24 domain-containing protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 93 of Transmembrane emp24 domain-containing protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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