Toll-like receptor 1

Intramolecular

A redox-regulated disulphide may form within Toll-like receptor 1 between cysteines 667 and 686. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7nt7

Structure name

solution structure of toll like receptor 1 (tlr1) tir domain

Structure deposition date

2021-03-09

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q15399

Residue number A

667

Residue number B

686

Peptide name

Toll-like receptor 1

Ligandability

Cysteine 667 of Toll-like receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.