Sonic hedgehog protein

Intramolecular

A redox-regulated disulphide may form within Sonic hedgehog protein between cysteines 102 and 183. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6pjv

Structure name

structure of human sonic hedgehog in complex with zinc and magnesium

Structure deposition date

2019-06-28

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

Q15465

Residue number A

102

Residue number B

183

Peptide name

Sonic hedgehog protein

Ligandability

Cysteine 102 of Sonic hedgehog protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.