Nuclear receptor coactivator 2

Intramolecular

A redox-regulated disulphide may form within Nuclear receptor coactivator 2 between cysteines 1065 and 303 (440 and 475 respectively in this structure).

Details

Redox score ?

nan

PDB code

5i4v

Structure name

discovery of novel, orally efficacious liver x receptor (lxr) beta agonists

Structure deposition date

2016-02-12

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q15596

Residue number A

1065

Residue number B

303

Peptide name

Nuclear receptor coactivator 2

Ligandability

Cysteine 1065 of Nuclear receptor coactivator 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 303 of Nuclear receptor coactivator 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Uncertain whether structure cysteine 440 has been assigned to correct residue.

Uncertain whether structure cysteine 475 has been assigned to correct residue.

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