ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Chitinase-3-like protein 2

Intramolecular
Cysteine 308 and cysteine 372
Cysteine 31 and cysteine 56
A redox-regulated disulphide may form within Chitinase-3-like protein 2 between cysteines 308 and 372.

Details

Redox score ?
84
PDB code
4p8u
Structure name
the crystal structures of ykl-39 in the absence of chitooligosaccharides was solved to resolutions of 2
Structure deposition date
2014-04-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q15782
Residue number A
308
Residue number B
372
Peptide name
Chitinase-3-like protein 2

Ligandability

Cysteine 308 of Chitinase-3-like protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 372 of Chitinase-3-like protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Chitinase-3-like protein 2 between cysteines 31 and 56.

Details

Redox score ?
80
PDB code
4ay1
Structure name
human ykl-39 is a pseudo-chitinase with retained chitooligosaccharide binding properties
Structure deposition date
2012-06-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q15782
Residue number A
31
Residue number B
56
Peptide name
Chitinase-3-like protein 2

Ligandability

Cysteine 31 of Chitinase-3-like protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 56 of Chitinase-3-like protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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