a tool for identifying drug-targetable redox-active disulphides

Syntaxin-binding protein 2

Intramolecular

Cysteine 44 and cysteine 45

A redox-regulated disulphide may form within Syntaxin-binding protein 2 between cysteines 44 and 45.

Details

Redox score ?

77

PDB code

Structure name

structure of human munc18-2

Structure deposition date

2013-10-21

Thiol separation (Å)

4

Half-sphere exposure sum ?

65

Minimum pK_a ?

7

% buried

60

Peptide accession

Residue number A

44

Residue number B

45

Peptide name

Syntaxin-binding protein 2

Ligandability

Cysteine 44 of Syntaxin-binding protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 45 of Syntaxin-binding protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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