C-C motif chemokine 15
Intermolecular
Cysteine 53 and cysteine 273 of C-C chemokine receptor type 1
Cysteine 93 and cysteine 24 of C-C chemokine receptor type 1
Cysteine 54 and cysteine 273 of C-C chemokine receptor type 1
Cysteine 54 and cysteine 24 of C-C chemokine receptor type 1
Cysteine 53 and cysteine 24 of C-C chemokine receptor type 1
Cysteine 93 and cysteine 273 of C-C chemokine receptor type 1
Cysteine 77 and cysteine 273 of C-C chemokine receptor type 1
Cysteine 77 and cysteine 24 of C-C chemokine receptor type 1
Intramolecular
Cysteine 53 and cysteine 77
Cysteine 64 and cysteine 104
More...Cysteine 54 and cysteine 93
Cysteine 53 and cysteine 54
Cysteine 54 and cysteine 77
Cysteine 77 and cysteine 93
Cysteine 53 and cysteine 93
7vl9 L 32 R 273
A redox-regulated disulphide may form between cysteine 53 of C-C motif chemokine 15 and cysteine 273 of C-C chemokine receptor type 1 (32 and 273 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7vl9
Structure name
cryo-em structure of the ccl15(26-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
53
Peptide B residue number
273
Ligandability
Cysteine 53 of C-C motif chemokine 15
Cysteine 273 of C-C chemokine receptor type 1
7vl9 L 72 R 24
A redox-regulated disulphide may form between cysteine 93 of C-C motif chemokine 15 and cysteine 24 of C-C chemokine receptor type 1 (72 and 24 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7vl9
Structure name
cryo-em structure of the ccl15(26-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
93
Peptide B residue number
24
Ligandability
Cysteine 93 of C-C motif chemokine 15
Cysteine 24 of C-C chemokine receptor type 1
7vla L 33 R 273
A redox-regulated disulphide may form between cysteine 54 of C-C motif chemokine 15 and cysteine 273 of C-C chemokine receptor type 1 (33 and 273 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7vla
Structure name
cryo-em structure of the ccl15(27-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
54
Peptide B residue number
273
Ligandability
Cysteine 54 of C-C motif chemokine 15
Cysteine 273 of C-C chemokine receptor type 1
7vla L 33 R 24
A redox-regulated disulphide may form between cysteine 54 of C-C motif chemokine 15 and cysteine 24 of C-C chemokine receptor type 1 (33 and 24 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7vla
Structure name
cryo-em structure of the ccl15(27-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
54
Peptide B residue number
24
Ligandability
Cysteine 54 of C-C motif chemokine 15
Cysteine 24 of C-C chemokine receptor type 1
7vla L 32 R 24
A redox-regulated disulphide may form between cysteine 53 of C-C motif chemokine 15 and cysteine 24 of C-C chemokine receptor type 1 (32 and 24 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7vla
Structure name
cryo-em structure of the ccl15(27-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
53
Peptide B residue number
24
Ligandability
Cysteine 53 of C-C motif chemokine 15
Cysteine 24 of C-C chemokine receptor type 1
7vl9 L 72 R 273
A redox-regulated disulphide may form between cysteine 93 of C-C motif chemokine 15 and cysteine 273 of C-C chemokine receptor type 1 (72 and 273 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
7vl9
Structure name
cryo-em structure of the ccl15(26-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
93
Peptide B residue number
273
Ligandability
Cysteine 93 of C-C motif chemokine 15
Cysteine 273 of C-C chemokine receptor type 1
7vl9 L 56 R 273
A redox-regulated disulphide may form between cysteine 77 of C-C motif chemokine 15 and cysteine 273 of C-C chemokine receptor type 1 (56 and 273 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
7vl9
Structure name
cryo-em structure of the ccl15(26-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
77
Peptide B residue number
273
Ligandability
Cysteine 77 of C-C motif chemokine 15
Cysteine 273 of C-C chemokine receptor type 1
7vla L 56 R 24
A redox-regulated disulphide may form between cysteine 77 of C-C motif chemokine 15 and cysteine 24 of C-C chemokine receptor type 1 (56 and 24 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
7vla
Structure name
cryo-em structure of the ccl15(27-92) bound ccr1-gi complex
Structure deposition date
2021-10-02
Thiol separation (Å)
10
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 15
Peptide B name
C-C chemokine receptor type 1
Peptide A accession
Q16663
Peptide B accession
P32246
Peptide A residue number
77
Peptide B residue number
24
Ligandability
Cysteine 77 of C-C motif chemokine 15
Cysteine 24 of C-C chemokine receptor type 1
2hcc A 6 A 30
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 53 and 77 (6 and 30 respectively in this structure).
Details
Redox score ?
87
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
42
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
53
Residue number B
77
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 53 of C-C motif chemokine 15
Cysteine 77 of C-C motif chemokine 15
2hcc A 17 A 57
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 64 and 104 (17 and 57 respectively in this structure).
Details
Redox score ?
85
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
64
Residue number B
104
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 64 of C-C motif chemokine 15
Cysteine 104 of C-C motif chemokine 15
2hcc A 7 A 46
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 54 and 93 (7 and 46 respectively in this structure).
Details
Redox score ?
82
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
54
Residue number B
93
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 54 of C-C motif chemokine 15
Cysteine 93 of C-C motif chemokine 15
2hcc A 6 A 7
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 53 and 54 (6 and 7 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
8
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
53
Residue number B
54
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 53 of C-C motif chemokine 15
Cysteine 54 of C-C motif chemokine 15
2hcc A 7 A 30
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 54 and 77 (7 and 30 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
41
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
54
Residue number B
77
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 54 of C-C motif chemokine 15
Cysteine 77 of C-C motif chemokine 15
2hcc A 30 A 46
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 77 and 93 (30 and 46 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
77
Residue number B
93
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 77 of C-C motif chemokine 15
Cysteine 93 of C-C motif chemokine 15
2hcc A 6 A 46
A redox-regulated disulphide may form within C-C motif chemokine 15 between cysteines 53 and 93 (6 and 46 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
2hcc
Structure name
solution structure of the human chemokine hcc-2, nmr, 30 structures
Structure deposition date
1998-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q16663
Residue number A
53
Residue number B
93
Peptide name
C-C motif chemokine 15
Ligandability
Cysteine 53 of C-C motif chemokine 15
Cysteine 93 of C-C motif chemokine 15
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